Evidence map›Paper›PMID 37086189›Full record

ArticleAmerican journal of hypertension2023

Peer Counselor Intervention for Reducing Mortality and/or Hospitalization in Adults With Hypertensive Urgency in Tanzania: A Pilot Study.

Godfrey A Kisigo, Frank Mgeta, Onike Mcharo, Elialilia Okello, Bahati Wajanga, Fredrick Kalokola, Graham Mtui, Radhika Sundararajan, Robert N Peck

Open access · greenAbstract read
In one paragraph

Article in American journal of hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Godfrey A KisigoCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-6454-3969
Frank MgetaDepartment of Internal Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania.
Onike McharoMwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania.
Elialilia OkelloMwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania.
Bahati WajangaDepartment of Internal Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania.
Fredrick KalokolaDepartment of Internal Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania.
Graham MtuiDepartment of Internal Medicine, Sekou Touré Referral Regional Hospital, Mwanza, Tanzania.
Radhika SundararajanCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Robert N PeckCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Bugando Medical Centre · TZCornell University · USMwanza Intervention Trials Unit · TZ

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
HIV, Sleep, Nocturnal Non-dipping, and Cardiovascular Disease: a Tanzanian CohortR01HL160332 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI PECK, ROBERT N · 2021 to 2025
$2.7M
Post-Doctoral Fellowship Training in HIV Clinical InvestigationD43TW011826 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI Daniel W Fitzgerald, Saidi Kapiga · 2021 to 2026
$1.9M
Expanding HIV testing among Ugandan adults who utilize traditional healersK23MH111409 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SUNDARARAJAN, RADHIKA LU · 2017 to 2021
$778k
Patient-Oriented Research in Global Cardiovascular Diseases and Interactions with HIVK24HL170902 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Robert N Peck · 2023 to 2026
$504k
FIC NIH HHS D43 TW009337FIC NIH HHS D43 TW011826NCATS NIH HHS UL1 TR002384NHLBI NIH HHS K24 HL170902NHLBI NIH HHS R01 HL160332NIH HHS D43 TW009337NIMH NIH HHS K23 MH111409
6 · The paper itself

Abstract

backgroundWorldwide, people with hypertensive urgency experience high rates of hospitalization and death due to medication non-adherence. Interventions to improve medication adherence and health outcomes after hypertensive urgency are urgently needed.

methodsThis prospective cohort assessed the effect of a peer counselor intervention-named Rafiki mwenye msaada-on the 1-year incidence of hospitalization and/or death among adults with hypertensive urgency in Mwanza, Tanzania. We enrolled 50 patients who presented with hypertensive urgency to 2 hospitals in Mwanza, Tanzania. All 50 patients received a Rafiki mwenye msaada an individual-level, time-limited case management intervention. Rafiki mwenye msaada aims to empower adult patients with hypertensive urgency to manage their high blood pressure. It consists of 5 sessions delivered over 3 months by a peer counselor. Outcomes were compared to historical controls.

resultsOf the 50 patients (median age, 61 years), 34 (68%) were female, and 19 (38%) were overweight. In comparison to the historical controls, the intervention cohort had a significantly lower proportion of patients with a secondary level of education (22% vs. 35%) and health insurance (40% vs. 87%). Nonetheless, the 1-year cumulative incidence of hospitalization and/or death was 18% in the intervention cohort vs. 35% in the control cohort (adjusted Hazard Ratio, 0.48, 95% CI 0.24-0.97; P = 0.041). Compared to historical controls, intervention participants maintained higher rates of medication use and clinic attendance at both 3- and 6-months but not at 12 months. Of intervention participants who survived and remained in follow-up, >90% reported good medication adherence at all follow-up time points.

conclusionOur findings support the hypothesis that a peer counselor intervention may improve health outcomes among adults living with hypertensive urgency. A randomized clinical trial is needed to evaluate the intervention's effectiveness.

Indexed as

CounselorsAdultFemaleHospitalizationHumansMaleMedication AdherenceMiddle AgedPilot ProjectsProspective StudiesTanzaniaadherenceblood pressurehospitalizationhypertensionhypertensive urgencymortalitypeer counselor interventionTanzania

Identifiers

PMID37086189
PMCPMC10345467
OpenAlexW4366742299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.