Evidence map›Paper›PMID 37085867›Full record

ArticleParticle and fibre toxicology2023

Lung-gut axis of microbiome alterations following co-exposure to ultrafine carbon black and ozone.

Md Habibul Hasan Mazumder, Jasleen Gandhi, Nairrita Majumder, Lei Wang, Robert Ian Cumming, Sydney Stradtman, Murugesan Velayutham, Quincy A Hathaway, Jonathan Shannahan, Gangqing Hu and 4 more

Abstract read
In one paragraph

Article in Particle and fibre toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  9. Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  10. Review
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  14. Maternal use of electronic cigarettes and impact on offspring: a double-hit model.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Md Habibul Hasan MazumderDepartment of Physiology, Pharmacology, and Toxicology, Center for Inhalation Toxicology (iTOX), School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Jasleen GandhiDepartment of Microbiology, School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Nairrita MajumderDepartment of Physiology, Pharmacology, and Toxicology, Center for Inhalation Toxicology (iTOX), School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Lei WangDepartment of Microbiology, School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Robert Ian CummingDepartment of Medicine, Duke University Medical Center, Durham, NC, 2927, USA.
Sydney StradtmanSchool of Health Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Murugesan VelayuthamDepartment of Physiology, Pharmacology, and Toxicology, Center for Inhalation Toxicology (iTOX), School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Quincy A HathawayHeart and Vascular Institute, School of Medicine, West Virginia University, Morgantown, WV, USA.
Jonathan ShannahanSchool of Health Sciences, Purdue University, West Lafayette, IN, 47907, USA.
Gangqing HuDepartment of Microbiology, School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Timothy R NurkiewiczDepartment of Physiology, Pharmacology, and Toxicology, Center for Inhalation Toxicology (iTOX), School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Robert M TigheDepartment of Medicine, Duke University Medical Center, Durham, NC, 2927, USA.
Eric E KelleyDepartment of Physiology, Pharmacology, and Toxicology, Center for Inhalation Toxicology (iTOX), School of Medicine, West Virginia University, Morgantown, WV, 26506, USA.
Salik HussainDepartment of Physiology, Pharmacology, and Toxicology, Center for Inhalation Toxicology (iTOX), School of Medicine, West Virginia University, Morgantown, WV, 26506, USA. salik.hussain@hsc.wvu.edu.

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI GARY O RANKIN · 2012 to 2026
$61.1M
WVU Flow Cytometry and Single Cell Core Facility (FCSCCF)P20GM121322 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Karen H Martin · 2018 to 2026
$22.4M
Inflammatory cross-talk between heat events and air pollutionR01ES031253 · NIEHS · WEST VIRGINIA UNIVERSITY · PI HUSSAIN, SALIK · 2020 to 2024
$3.5M
CXCL10/CXCR3 regulation of ozone-induced epithelial permeabilityR01ES027574 · NIEHS · DUKE UNIVERSITY · PI TIGHE, ROBERT MATTHEW · 2018 to 2022
$3.1M
Compromised Resolution of Inflammation following Nanoparticle Exposure in Metabolic SyndromeR01ES033173 · NIEHS · PURDUE UNIVERSITY · PI Jonathan Henry Shannahan · 2022 to 2026
$1.7M
NIEHS NIH HHS R01 ES027574NIEHS NIH HHS R01 ES031253NIEHS NIH HHS R01 ES033173NIGMS NIH HHS P20 GM103434NIGMS NIH HHS P20 GM121322
6 · The paper itself

Abstract

backgroundMicrobial dysbiosis is a potential mediator of air pollution-induced adverse outcomes. However, a systemic comparison of the lung and gut microbiome alterations and lung-gut axis following air pollution exposure is scant. In this study, we exposed male C57BL/6J mice to inhaled air, CB (10 mg/m

resultsMultiple CB + O

conclusionOur study confirms distinct gut and lung microbiome alterations after CB + O

Indexed as

MicrobiotaOzoneAnimalsLungMaleMiceMice, Inbred C57BLRNA, MessengerSootOzoneRNA, MessengerSootCo-exposureEPRInflammationInhalationMicrobial dysbiosisOzoneUltrafine carbon black

Identifiers

PMID37085867
PMCPMC10122302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.