Evidence map›Paper›PMID 37085860›Full record

ArticleAIDS research and therapy2023

A cross-sectional analysis of psychosocial and structural barriers and facilitators associated with PrEP use among a sample of transgender women in Chicago, IL.

Lisa M Kuhns, Judy Perloff, Amy K Johnson, Josie Lynne Paul, Kevin Pleasant, Kaiji Evans, Damian J Denson, Deborah J Gelaude, Patricia A Bessler, Rose Diskin and 3 more

Abstract read
In one paragraph

Article in AIDS research and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Validation of the PrEP Use Self-Efficacy (PrEP-Use) Scale Among Sexual Minority Men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
    Trial
  2. Article
  3. Article
  4. Review
  5. Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lisa M KuhnsDepartment of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA. lkuhns@luriechildrens.org.
Judy PerloffChicago House and Social Service Agency, Chicago, IL, USA.
Amy K JohnsonDepartment of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Josie Lynne PaulChicago House and Social Service Agency, Chicago, IL, USA.
Kevin PleasantChicago House and Social Service Agency, Chicago, IL, USA.
Kaiji EvansChicago House and Social Service Agency, Chicago, IL, USA.
Damian J DensonCenters for Disease Control and Prevention, Atlanta, GA, USA.
Deborah J GelaudeCenters for Disease Control and Prevention, Atlanta, GA, USA.
Patricia A BesslerCenters for Disease Control and Prevention, Atlanta, GA, USA.
Rose DiskinDivision of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Marbella CervantesDivision of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Robert GarofaloDepartment of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Anna L HottonDepartment of Medicine, University of Chicago, Chicago, IL, USA.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
CDC HHS U01PS005140NCATS NIH HHS UL1 TR001422NCHHSTP CDC HHS U01 PS005140
6 · The paper itself

Abstract

backgroundExpanding pre-exposure prophylaxis (PrEP) among transgender women in the United States is an important strategy to meet national HIV prevention goals, however self-reported use of PrEP is low in this group.

methodsThis study reports the findings of a cross-sectional analysis of the relationship of barriers as well as facilitators to recent PrEP use among transgender women enrolled in an evaluation of the TransLife Care project (Chicago, Illinois), a structural intervention designed to meet basic needs. We computed multivariable prevalence ratios for barriers, facilitators and recent PrEP use, controlling for demographics.

resultsFindings suggest that psychosocial and structural barriers, including moderate/high alcohol use, stimulant use, and history of incarceration were all positively associated with recent PrEP use among urban transgender women. In addition, a psychosocial facilitator, gender affirmation, was positively associated with recent PrEP use, while, while collective self-esteem, a was negatively associated with it. Finally, common indications for PrEP have high sensitivity, but low specificity and predictive value for identifying those on PrEP.

conclusionWe conclude that despite a large gap in PrEP use among those with indications, individuals experiencing psychosocial and structural barriers are more likely to use PrEP, and facilitators, such as psychological sense of affirmed gender may support its use.

trial registrationN/A.

Indexed as

Pre-Exposure ProphylaxisTransgender PersonsAdolescentAdultChicagoCross-Sectional StudiesFemaleHumansMaleYoung AdultHIVPre-exposure prophylaxisTransgender women

Identifiers

PMID37085860
PMCPMC10122350

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.