Evidence map›Paper›PMID 37085841›Full record

ArticleFluids and barriers of the CNS2023

A year in review: brain barriers and brain fluids research in 2022.

Richard F Keep, Hazel C Jones, Mark G Hamilton, Lester R Drewes

Open access · goldAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Fluids and barriers of the CNS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Richard F KeepDepartment of Neurosurgery, University of Michigan, R5018 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. rkeep@umich.edu.
Hazel C Jones, Bicester, OX26 1UF, UK.
Mark G HamiltonDepartment of Clinical Neurosciences, Division of Neurosurgery, University of Calgary, Alberta, Canada.
Lester R DrewesDepartment of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
OXGENE (United Kingdom) · GBUniversity of Calgary · CAUniversity of Michigan–Ann Arbor · USUniversity of Minnesota, Duluth · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This aim of this editorial is to highlight progress made in brain barrier and brain fluid research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers (choroid plexus and meninges), signaling within the neurovascular unit and elements of the brain fluid systems. It further discusses how brain barriers and brain fluid systems are impacted in CNS diseases, their role in disease progression and progress being made in treating such diseases.

Indexed as

Blood-Brain BarrierBrainCerebrospinal FluidChoroid PlexusBlood-brain barrierBrain endotheliumCerebrospinal fluid, choroid plexus, drug deliveryGlymphatics, hydrocephalus, neurovascular unit

Identifiers

PMID37085841
PMCPMC10120509
OpenAlexW4366742647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.