Evidence map›Paper›PMID 37085812›Full record

Trial reportBMC surgery2023

Colectomy reconstruction for ulcerative colitis in Sweden and England: a multicenter prospective comparison between ileorectal anastomosis and ileal pouch-anal anastomosis after colectomy in patients with ulcerative colitis. (CRUISE-study).

Anton Risto, Caroline Nordenvall, Mohammed Deputy, Maria Hermanson, Ulrik Lindforss, Mattias Block, Omar Faiz, Pär Myrelid

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialControlled Clinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05628701 (Colectomy Reconstruction for Ulcerative Colitis In Sweden and England), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05628701 narecruitingnot on this map

Colectomy Reconstruction for Ulcerative Colitis In Sweden and England: a Multicenter Prospective Comparison Between Ileorectal Anastomosis and Ileal Pouch-Anal Anastomosis After Colectomy in Patients With Ulcerative Colitis.

TypeinterventionalSponsorLinkoeping UniversityRan2017 to 2029Enrolled100ConditionsUlcerative Colitis, Inflammatory Bowel Diseases, Ileostomy - StomaArmsIleorectal anastomosis (IRA), Ileal pouch anal anastomosis (IPAA), ileostomy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Chance of pouch surgery after colectomy for ulcerative colitis based on pelvic pouch volumes at the colectomy hospital, a Swedish national cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Anton RistoDivision of Surgery, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University Hospital Linköping, 581 85, Linköping, Sweden. anton.risto@liu.se.
Caroline NordenvallDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Mohammed DeputySt Mark's Hospital and Academic Institute, Harrow, UK.
Maria HermansonDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ulrik LindforssDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Mattias BlockDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Omar FaizCenter for Digestive Disease, Division of Coloproctology, Karolinska University Hospital, Stockholm, Sweden.
Pär MyrelidDivision of Surgery, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University Hospital Linköping, 581 85, Linköping, Sweden.
Karolinska University Hospital · SEUniversity of Gothenburg · SEImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are no prospective trials comparing the two main reconstructive options after colectomy for Ulcerative colitis, ileal pouch anal anastomosis and ileorectal anastomosis. An attempt on a randomized controlled trial has been made but after receiving standardized information patients insisted on choosing operation themselves.

methodsAdult Ulcerative colitis patients subjected to colectomy eligible for both ileal pouch anastomosis and ileorectal anastomosis are asked to participate and after receiving standardized information the get to choose reconstructive method. Patients declining reconstruction or not considered eligible for both methods will be followed as controls. The CRUISE study is a prospective, non-randomized, multi-center, open-label, controlled trial on satisfaction, QoL, function, and complications between ileal pouch anal anastomosis and ileorectal anastomosis. DISCUSSION: Reconstruction after colectomy is a morbidity-associated as well as a resource-intensive activity with the sole purpose of enhancing function, QoL and patient satisfaction. The aim of this study is to provide the best possible information on the risks and benefits of each reconstructive treatment.

trial registrationClinicalTrials.gov Identifier: NCT05628701.

Indexed as

Colitis, UlcerativeProctocolectomy, RestorativeAdultAnastomosis, SurgicalColectomyHumansQuality of LifeSwedenIleal pouch anal anastomosisIleoanal anastomosisReconstructive surgeryUlcerative colitis

Identifiers

PMID37085812
PMCPMC10122388
OpenAlexW4366723924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.