ArticleThe ISME journal2023
Cuticle supplementation and nitrogen recycling by a dual bacterial symbiosis in a family of xylophagous beetles.
Article in The ISME journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Metabolic plasticity supports a flexible nutritional symbiosis in Cardiocondyla ants.Nature communications · 2026Article
- Regulatory mechanisms of nitrogen homeostasis in insect growth and development.Insect science · 2026Review
- Review
- A bacterial symbiont and a plant virus enhance insect fitness by inducing physical defenses against fungal parasites.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Gut microbiota-mediated nitrogen recycling in the white Grub Holotrichia longipennis: A model for microbiome-targeted pest control.World journal of microbiology & biotechnology · 2026Article
- Convergent extreme reductive evolution in ancient planthopper symbioses.Nature communications · 2026Article
- Gut microbiome convergence and functional adaptation underlie the evolution of predation in stink bugs (Heteroptera: Pentatomidae).Microbiome · 2026Article
- The Microbiome as a Protagonist of Xylophagous Insects in Adaptation to Environmental Conditions and Climate Change.International journal of molecular sciences · 2025Review
- Analysis of the Bacterial Community and Fatty Acid Composition in the Bacteriome of the Lac InsectMicroorganisms · 2025Article
- Analysis of the tripartite interactions between two bacterial symbionts, a novelMicrobiology spectrum · 2025Article
- Accelerated Pseudogenization in the Ancient Endosymbionts of Giant Scale Insects.Molecular biology and evolution · 2025Article
- Influence of the Chemical Properties of Cereal Grains on the Structure and Metabolism of the Bacteriome ofInternational journal of molecular sciences · 2024Article
- With a little help from my friends: the roles of microbial symbionts in insect populations and communities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Comparative Transcriptomics of Fat Bodies between Symbiotic and Quasi-Aposymbiotic Adult Females ofInternational journal of molecular sciences · 2024Article
- Intracellular symbiont Symbiodolus is vertically transmitted and widespread across insect orders.The ISME journal · 2024Article
- SeqCode in the golden age of prokaryotic systematics.The ISME journal · 2024Article
- Evolutionary history of tyrosine-supplementing endosymbionts in pollen-feeding beetles.The ISME journal · 2024Article
- Cuticle supplementation and nitrogen recycling by a dual bacterial symbiosis in a family of xylophagous beetles.The ISME journal · 2023Article
- Endosymbiosis allowsFrontiers in microbiology · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many insects engage in stable nutritional symbioses with bacteria that supplement limiting essential nutrients to their host. While several plant sap-feeding Hemipteran lineages are known to be simultaneously associated with two or more endosymbionts with complementary biosynthetic pathways to synthesize amino acids or vitamins, such co-obligate symbioses have not been functionally characterized in other insect orders. Here, we report on the characterization of a dual co-obligate, bacteriome-localized symbiosis in a family of xylophagous beetles using comparative genomics, fluorescence microscopy, and phylogenetic analyses. Across the beetle family Bostrichidae, most investigated species harbored the Bacteroidota symbiont Shikimatogenerans bostrichidophilus that encodes the shikimate pathway to produce tyrosine precursors in its severely reduced genome, likely supplementing the beetles' cuticle biosynthesis, sclerotisation, and melanisation. One clade of Bostrichid beetles additionally housed the co-obligate symbiont Bostrichicola ureolyticus that is inferred to complement the function of Shikimatogenerans by recycling urea and provisioning the essential amino acid lysine, thereby providing additional benefits on nitrogen-poor diets. Both symbionts represent ancient associations within the Bostrichidae that have subsequently experienced genome erosion and co-speciation with their hosts. While Bostrichicola was repeatedly lost, Shikimatogenerans has been retained throughout the family and exhibits a perfect pattern of co-speciation. Our results reveal that co-obligate symbioses with complementary metabolic capabilities occur beyond the well-known sap-feeding Hemiptera and highlight the importance of symbiont-mediated cuticle supplementation and nitrogen recycling for herbivorous beetles.
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