Evidence map›Paper›PMID 37085533›Full record

ArticleScientific data2023

A Large-scale Synthetic Pathological Dataset for Deep Learning-enabled Segmentation of Breast Cancer.

Kexin Ding, Mu Zhou, He Wang, Olivier Gevaert, Dimitris Metaxas, Shaoting Zhang

Abstract readDataset
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Integrative and deep learning-based prediction of therapy response in ovarian cancer.Journal of experimental & clinical cancer research : CR · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kexin DingDepartment of Computer Science, University of North Carolina at Charlotte, Charlotte, NC, 28262, USA.ORCID 0000-0002-3561-3195
Mu ZhouSensebrain Research, San Jose, CA, 95131, USA.
He WangDepartment of Pathology, Yale University, New Haven, CT, 06520, USA.
Olivier GevaertStanford Center for Biomedical Informatics Research, Department of Medicine and Biomedical Data Science, Stanford University, Stanford, CA, 94305, USA.
Dimitris MetaxasDepartment of Computer Science, Rutgers University, New Brunswick, NJ, 08901, USA.
Shaoting ZhangShanghai Artificial Intelligence Laboratory, Shanghai, 200232, China. zhangshaoting@pjlab.org.cn.

Funding

Multi-scale modeling of glioma for the prediction of treatment response, treatment monitoring and treatment allocationR01CA260271 · NCI · STANFORD UNIVERSITY · PI GEVAERT, OLIVIER · 2021 to 2025
$3.1M
NCI NIH HHS R01 CA260271
6 · The paper itself

Abstract

The success of training computer-vision models heavily relies on the support of large-scale, real-world images with annotations. Yet such an annotation-ready dataset is difficult to curate in pathology due to the privacy protection and excessive annotation burden. To aid in computational pathology, synthetic data generation, curation, and annotation present a cost-effective means to quickly enable data diversity that is required to boost model performance at different stages. In this study, we introduce a large-scale synthetic pathological image dataset paired with the annotation for nuclei semantic segmentation, termed as Synthetic Nuclei and annOtation Wizard (SNOW). The proposed SNOW is developed via a standardized workflow by applying the off-the-shelf image generator and nuclei annotator. The dataset contains overall 20k image tiles and 1,448,522 annotated nuclei with the CC-BY license. We show that SNOW can be used in both supervised and semi-supervised training scenarios. Extensive results suggest that synthetic-data-trained models are competitive under a variety of model training settings, expanding the scope of better using synthetic images for enhancing downstream data-driven clinical tasks.

Indexed as

Breast NeoplasmsDeep LearningPrivacyWorkflowFemaleHumansImage Processing, Computer-AssistedSemantics

Identifiers

PMID37085533
PMCPMC10121551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.