Evidence map›Paper›PMID 37085253›Full record

ArticleKidney international2023

Resolving a paradox between mouse and man: a genetic link between TLR7 and the pathogenesis of human lupus nephritis.

Shaun W Jackson, Brad H Rovin

Open access · greenAbstract readComment
In one paragraph

Article in Kidney international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shaun W JacksonSeattle Children's Research Institute, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA; Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA. Electronic address: shaun.jackson@seattlechildrens.org.
Brad H RovinNephrology Division, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
The Ohio State University Wexner Medical Center · USUniversity of Washington · US

Funding

RESEARCH TRAINING IN RHEUMATOLOGYT32AR007108 · NIAMS · UNIVERSITY OF WASHINGTON · PI Shaun Jackson, Tomas M Mustelin · 1986 to 2026
$6.6M
Mechanistic insights into systemic lupus erythematosus (SLE) pathogenesis from inborn errors of immunityR01AR073938 · NIAMS · SEATTLE CHILDREN'S HOSPITAL · PI Shaun William Jackson · 2019 to 2026
$4.0M
Predictive Biomarkers for disease activity and organ damage in patients with lupusR01AR071947 · NIAMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OATES, JAMES C, ROVIN, BRAD H · 2018 to 2022
$3.2M
Impact of Loss-of-function NADPH Oxidase Variants on B-Cell Activation in SLER01AR075813 · NIAMS · SEATTLE CHILDREN'S HOSPITAL · PI JACKSON, SHAUN WILLIAM · 2021 to 2025
$2.8M
NIAMS NIH HHS R01 AR071947NIAMS NIH HHS R01 AR073938NIAMS NIH HHS R01 AR075813NIAMS NIH HHS T32 AR007108
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lupus NephritisToll-Like Receptor 7Antibodies, AntinuclearAutoantibodiesHumansAntibodies, AntinuclearAutoantibodiesTLR7 protein, humanToll-Like Receptor 7antinuclear autoantibodiesautoreactive B cellshuman geneticslupus nephritistoll-like receptors

Identifiers

PMID37085253
PMCPMC11639588
OpenAlexW4366437845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.