Evidence map›Paper›PMID 37084943›Full record

ArticleEnvironmental research2023

Intermediate and long-term exposure to air pollution and temperature and the extracellular microRNA profile of participants in the normative aging study (NAS).

Mahdieh Danesh Yazdi, Feiby L Nassan, Anna Kosheleva, Cuicui Wang, Zongli Xu, Qian Di, Weeberb J Requia, Nicole T Comfort, Haotian Wu, Louise C Laurent and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Climate change and epigenetic biomarkers in allergic and airway diseases.The Journal of allergy and clinical immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Mahdieh Danesh YazdiProgram in Public Health, Department of Family, Population, and Preventive Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA. Electronic address: mahdieh.daneshyazdi@stonybrookmedicine.edu.
Feiby L NassanDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Biogen Inc, Cambridge, MA, USA.
Anna KoshelevaDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.
Cuicui WangDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.
Zongli XuLaboratory of Molecular Carcinogenesis and Biostatistics Branch, National Institute of Environmental Health Sciences, Durham, NC, USA.
Qian DiVanke School of Public Health, Tsinghua University, Beijing, China.
Weeberb J RequiaSchool of Public Policy and Government, Fundação Getúlio Vargas, Brasília, Distrito Federal, Brazil.
Nicole T ComfortDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health, New York, NY, USA.
Haotian WuDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health, New York, NY, USA.
Louise C LaurentDepartment of Obstetrics, Gynecology, & Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Peter DeHoffDepartment of Obstetrics, Gynecology, & Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Pantel VokonasDepartment of Veterans Affairs, Boston, MA, USA; Department of Medicine, Boston University Chobanian and Avidisian School of Medicine, Boston, MA, USA.
Andrea A BaccarelliDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health, New York, NY, USA.
Joel D SchwartzDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Columbia University · USHarvard University · USUniversity of California San Diego · USBiogen (United States) · USBoston University · USFundação Getulio Vargas · BRMassachusetts Department of Public Health · USNational Institute of Environmental Health Sciences · USVanke (China) · CN

Funding

Air Particulate, Metals, and Cognitive Performance in an Aging Cohort- Roles of Circulating Extracellular Vesicles and Non-coding RNAsR01ES027747 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI SCHWARTZ, JOEL D · 2017 to 2021
$3.7M
Intramural NIH HHS Z99 ES999999NIEHS NIH HHS R01 ES027747
6 · The paper itself

Abstract

backgroundThe molecular effects of intermediate and long-term exposure to air pollution and temperature, such as those on extracellular microRNA (ex-miRNA) are not well understood but may have clinical consequences.

objectivesTo assess the association between exposure to ambient air pollution and temperature and ex-miRNA profiles.

methodsOur study population consisted of 734 participants in the Normative Aging Study (NAS) between 1999 and 2015. We used high-resolution models to estimate four-week, eight-week, twelve-week, six-month, and one-year moving averages of PM

resultsWe found 151 significant associations between levels of PM

conclusionOur results show that intermediate and long-term exposure to all our exposures of interest were associated with changes in the ex-miRNA profile of study participants. Further studies on environmental risk factors and ex-miRNAs are warranted.

Indexed as

Air PollutantsAir PollutionMicroRNAsOzoneAgingEnvironmental ExposureHumansNitrogen DioxideParticulate MatterPlant ExtractsTemperatureAir PollutantsMicroRNAsnasNitrogen DioxideOzoneParticulate MatterPlant ExtractsAir pollutionAmbient temperaturemicroRNANitrogen dioxideOzoneParticulate matter

Identifiers

PMID37084943
PMCPMC10335853
OpenAlexW4366742596

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.