Evidence map›Paper›PMID 37084355›Full record

ArticleGlobal spine journal2023

Avoiding Spinal Implant Failures in Osteoporotic Patients: A Narrative Review.

Friederike Schömig, Luis Becker, Lukas Schönnagel, Anna Völker, Alexander C Disch, Klaus John Schnake, Matthias Pumberger

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. A novel UHMWPE anchor for improving the pullout resistance of pedicle screws.Frontiers in bioengineering and biotechnology · 2026
    Article
  8. Article
  9. Article
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  11. Loosening of stand-alone ALIF versus TLIF in degenerated lumbar human spines: an in vitro biomechanical study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Observational
  19. Personalized Approaches to Spine Surgery.International journal of spine surgery · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Friederike SchömigCenter for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-9224-7363
Luis BeckerCenter for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-5549-0479
Lukas SchönnagelCenter for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Anna VölkerDepartment of Orthopaedic, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.
Alexander C DischUniversity Comprehensive Spine Center, University Center for Orthopedics, Traumatology and Plastic Surgery, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.ORCID 0000-0001-8414-4041
Klaus John SchnakeCenter for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St Marien gGmbH, Erlangen, Germany.
Matthias PumbergerCenter for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEMalteser Waldkrankenhaus Erlangen · DEUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designNarrative review.

objectivesWith an aging population, the prevalence of osteoporosis is continuously rising. As osseous integrity is crucial for bony fusion and implant stability, previous studies have shown osteoporosis to be associated with an increased risk for implant failure and higher reoperation rates after spine surgery. Thus, our review's purpose was to provide an update of evidence-based solutions in the surgical treatment of osteoporosis patients.

methodsWe summarize the existing literature regarding changes associated with decreased bone mineral density (BMD) and resulting biomechanical implications for the spine as well as multidisciplinary treatment strategies to avoid implant failures in osteoporotic patients.

resultsOsteoporosis is caused by an uncoupling of the bone remodeling cycle based on an unbalancing of bone resorption and formation and resulting reduced BMD. The reduction in trabecular structure, increased porosity of cancellous bone and decreased cross-linking between trabeculae cause a higher risk of complications after spinal implant-based surgeries. Thus, patients with osteoporosis require special planning considerations, including adequate preoperative evaluation and optimization. Surgical strategies aim towards maximizing screw pull-out strength, toggle resistance, as well as primary and secondary construct stability.

conclusionsAs osteoporosis plays a crucial role in the fate of patients undergoing spine surgery, surgeons need to be aware of the specific implications of low BMD. While there still is no consensus on the best course of treatment, multidisciplinary preoperative assessment and adherence to specific surgical principles help reduce the rate of implant-related complications.

Indexed as

bone densityosteoporosispedicle screwsrevisionspine

Identifiers

PMID37084355
PMCPMC10177307
OpenAlexW4366606473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.