Evidence map›Paper›PMID 37084348›Full record

ArticleGlobal spine journal2023

Spondylodiscitis in Geriatric Patients: What Are the Issues?

Christian Herren, Nicolas Heinz von der Hoeh, Stefan Zwingenberger, Daniel Sauer, Norma Jung, Philipp Pieroh, Steffen Drange, Matthias Pumberger, Max J Scheyerer, and Spine Section of the German Society for Orthopaedics and Trauma

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The conundrum of finding an optimal spondylodiscitis treatment pathway: how do treatments affect readmission rates?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. [Antibiotics (Basel, Switzerland) · 2024
    Article
  9. Microbiological Profiles of Patients with Spondylodiscitis.Antibiotics (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Christian HerrenDepartment of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University, Germany.
Nicolas Heinz von der HoehDepartment of Orthopedic, Trauma and Plastic Surgery, University Hospital Leipzig, Germany.ORCID 0000-0003-1928-5686
Stefan ZwingenbergerUniversity Center of Orthopedic, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus at TU Dresden, Germany.
Daniel SauerSpinecenter, Schön Klinik Munich Harlaching University, Deutschland.
Norma JungDepartment I of Internal Medicine, Medical Faculty, University Hospital of Cologne, University of Cologne, Germany.
Philipp PierohDepartment of Orthopedic, Trauma and Plastic Surgery, University Hospital Leipzig, Germany.
Steffen DrangeDepartment of Orthopaedic Surgery, Klinikum Magdeburg gGmbH, Germany.
Matthias PumbergerSpine Department, Center for Musculoskeletal Surgery, Charité University Medicine BerlinUniversity, Germany.
Max J ScheyererDepartment of Orthopedic and Trauma Surgery, Medical Faculty, University of Cologne, Germany.ORCID 0000-0003-1392-3990
and Spine Section of the German Society for Orthopaedics and Trauma
University Hospital Leipzig · DEUniversity of Cologne · DECharité - Universitätsmedizin Berlin · DEKlinikum Magdeburg · DERWTH Aachen University · DESchön Klinik München Harlaching · DEUniversity Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designReview article.

objectivesA review of literature on the treatment of pyogenic spondylodiscitis in geriatric patients was performed with the aim to give an overview about these special patients and a recommendation on necessary diagnostics as well as conservative and operative treatment options.

methodsA systematic computerized literature search was done by the spondylodiscitis working group of the German Society for Orthopedics and Trauma Surgery.

resultsSpondylodiscitis has an increasing incidence by age with a peak at 75 years or older. The 1-year mortality without an appropriate treatment is with 15 to 20% extremely high. Pathogen detection is the essential diagnostic step and the basis for a sufficient antibiotic treatment. Geriatric patients have initially less elevated inflammatory parameters. Compared to younger patients. They have a longer length of hospital stay and take longer for CRP normalization. Even the outcome between conservative and operative treatment is comparable after one year. Patients with spinal instability, immobilizing pain, epidural abscess, and newly emerged neurological deficits should be considered for operative treatment.

conclusionsThe treatment of geriatric patients with pyogenic spondylodiscitis must take into account that these patients usually have multiple comorbidities. The main goals are resistance-based antibiotics and the shortest possible time of immobilization of the patient.

Indexed as

comorbiditiesconservativegeriatric patientsoperativeresistance-based antibioticsspondylodiscitis

Identifiers

PMID37084348
PMCPMC10177302
OpenAlexW4366606413

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.