ArticleResearch on child and adolescent psychopathology2023
Neural Predictors of Improvement With Cognitive Behavioral Therapy for Adolescents With Depression: An Examination of Reward Responsiveness and Emotion Regulation.
Article in Research on child and adolescent psychopathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review.Journal of affective disorders · 2026Pooled it
- Neuropsychological Mechanisms Associated with the Effectiveness of AI-Delivered Health Promotion Programs: A Comprehensive Meta-Analysis.Brain sciences · 2026Review
- Mapping the Digital Mind: A Meta-Analysis of EEG Biomarkers in Cognition, Emotion, and Mental Health.Brain sciences · 2026Review
- Social Reward Responsiveness Moderates the Association between Perceived Social Competence and Depressive Symptoms in Adolescents.Research on child and adolescent psychopathology · 2026Article
- Interpersonal Contributors to Depression in Sexual Minority Adolescents: An Examination of Exposure to Acute Stressors and Neural Reactivity to Interpersonal Emotional Images.Developmental psychobiology · 2026Article
- Age-Related Differences and Effects of Internalizing Symptoms on Aperiodic Neural Activity in Adolescents.Psychophysiology · 2026Article
- Neuroscientific Framework of Cognitive-Behavioral Interventions for Mental Health Across Diverse Cultural Populations: A Systematic Review of Effectiveness, Delivery Methods, and Engagement.European journal of investigation in health, psychology and education · 2025Review
- Emotion and Executive Dysfunction in Young Children with Disruptive Behavior Disorders: The Role of Cardiac Autonomic Balance.Journal of psychopathology and behavioral assessment · 2025Article
- Differences in Children and Adolescents with Depression before and after a Remediation Program: An Event-Related Potential Study.Brain sciences · 2024Article
- Reduced reward responsiveness and depression vulnerability: Consideration of social contexts and implications for intervention.Psychophysiology · 2024Review
- Social and Monetary Reward Processing in Youth with Early Emerging Personality Pathology: An RDoC-Informed Study.Research on child and adolescent psychopathology · 2024Article
- Delta-Beta Coupling in Adolescents with Depression: A Preliminary Examination of Associations with Age, Symptoms, and Treatment Outcomes.Journal of psychophysiology · 2024Article
- Neural markers of emotion regulation difficulties in adolescent depression and risk for depression.Journal of mood and anxiety disorders · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Earlier depression onsets are associated with more debilitating courses and poorer life quality, highlighting the importance of effective early intervention. Many youths fail to improve with evidence-based treatments for depression, likely due in part to heterogeneity within the disorder. Multi-method assessment of individual differences in positive and negative emotion processing could improve predictions of treatment outcomes. The current study examined self-report and neurophysiological measures of reward responsiveness and emotion regulation as predictors of response to cognitive-behavioral therapy (CBT). Adolescents (14-18 years) with depression (N = 70) completed monetary reward and emotion regulation tasks while electroencephalogram (EEG) was recorded, and self-report measures of reward responsiveness, emotion regulation, and depressive symptoms at intake. Adolescents then completed a 16-session group CBT program, with depressive symptoms and clinician-rated improvement assessed across treatment. Lower reward positivity amplitudes, reflecting reduced neural reward responsiveness, predicted lower depressive symptoms with treatment. Larger late positive potential residuals during reappraisal, potentially reflecting difficulty with emotion regulation, predicted greater clinician-rated improvement. Self-report measures were not significant predictors. Results support the clinical utility of EEG measures, with impairments in positive and negative emotion processing predicting greater change with interventions that target these processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.