Evidence map›Paper›PMID 37084161›Full record

ArticleEmergency radiology2023

Low concordance between CTPA and echocardiography in identification of right ventricular strain in PERT patients with acute pulmonary embolism.

Mads Dam Lyhne, Nicholas Giordano, David Dudzinski, Jasmine Torrey, Grace Wang, Hui Zheng, Blair Alden Parry, Mannudeep K Kalra, Christopher Kabrhel

Erratum issuedAbstract read
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In one paragraph

Article in Emergency radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Home Treatment of Patients with Pulmonary Embolism: A Single Center 10-Year Experience from Ljubljana Registry.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mads Dam LyhneCenter for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5279-260X
Nicholas GiordanoCenter for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
David DudzinskiDepartment of Cardiology, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-9363-9345
Jasmine TorreyCenter for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Grace WangCenter for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Hui ZhengBiostatistics Center, Massachusetts General Hospital, Boston, MA, USA.
Blair Alden ParryCenter for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Mannudeep K KalraDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-9938-7476
Christopher KabrhelCenter for Vascular Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA. ckabrhel@partners.org.ORCID http://orcid.org/0000-0002-8699-7176

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRight ventricular strain (RVS) is used to risk stratify patients with acute pulmonary embolism (PE) and influence treatment decisions. Guidelines suggest that either computed tomography pulmonary angiography (CTPA) or transthoracic echocardiography (TTE) can be used to assess RVS. We sought to determine how often CTPA and TTE yield discordant results and to assess the test characteristics of CTPA compared to TTE.

methodsWe analyzed data from a single-center registry of PE cases severe enough to warrant activation of the hospital's Pulmonary Embolism Response Team (PERT). We defined RVS as a right ventricular to left ventricular ratio (RV/LV) ≥ 1 or radiologist's interpretation of RVS on CTPA or as the presence of either RV dilation, hypokinesis, or septal bowing on TTE.

resultsWe included 554 patients in our analysis, of whom 333 (60%) had concordant RVS findings on CTPA and TTE. Using TTE as the reference standard, CTPA had a sensitivity of 95% (95% CI 92-97%) and a specificity of 4% (95% CI 2-8%) for identifying RVS.

conclusionsIn a selected population of patients with acute PE for which PERT was activated, CTPA is highly sensitive but not specific for the detection of RVS when compared to TTE.

Indexed as

Pulmonary EmbolismAcute DiseaseEchocardiographyHeart VentriclesHumansAccuracyComputed tomographyPulmonary circulationRight ventricular functionRisk stratification

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.