Evidence map›Paper›PMID 37084148›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2023

The Promise of Niacin in Neurology.

Emily Wuerch, Gloria Roldan Urgoiti, V Wee Yong

Open access · bronzeAbstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Dual-Acting Vitamin BJournal of medicinal chemistry · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Vitamin abnormalities in neuropathic corneal pain.Eye and vision (London, England) · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Oxidative Stress in Brain Function.Antioxidants (Basel, Switzerland) · 2025
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emily WuerchHotchkiss Brain Institute, 3330 Hospital Drive NW, Calgary, AB, Canada.
Gloria Roldan UrgoitiHotchkiss Brain Institute, 3330 Hospital Drive NW, Calgary, AB, Canada.
V Wee YongHotchkiss Brain Institute, 3330 Hospital Drive NW, Calgary, AB, Canada. vyong@ucalgary.ca.ORCID 0000-0002-2600-3563
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Niacin (vitamin B3) is an essential nutrient that treats pellagra, and prior to the advent of statins, niacin was commonly used to counter dyslipidemia. Recent evidence has posited niacin as a promising therapeutic for several neurological disorders. In this review, we discuss the biochemistry of niacin, including its homeostatic roles in NAD

Indexed as

Alzheimer DiseaseNervous System DiseasesNeurologyNiacinPellagraAmyloid beta-PeptidesHumansAmyloid beta-PeptidesNiacinHydroxycarboxylic acid receptor (Hcar)2ImmunomodulationNAD+/NADPNeurological diseasesNiacin treatmentPhagocytosis

Identifiers

PMID37084148
PMCPMC10457276
OpenAlexW4366603148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.