ArticleClinical research in cardiology : official journal of the German Cardiac Society2024
Factors associated with changes in echocardiographic parameters following kidney transplantation.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Cardiorespiratory fitness and left ventricular recovery after kidney transplantation: evidence, gaps, and future directions.Renal failure · 2026Review
- Left Ventricular Hypertrophy After Renal Transplantation: Systematic Review and Meta-analysis.Transplantation direct · 2024Article
- Echocardiographic manifestations in end-stage renal disease.Heart failure reviews · 2024Review
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8 authors at 2 institutions in 1 country.
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Abstract
backgroundChronic kidney disease leads to cardiac remodelling of multifactorial origin known as "uraemic cardiomyopathy", the reversibility of which after kidney transplantation (KT) remains controversial. Our objectives were to assess, in the modern era, changes in echocardiographic parameters following KT and identify predictive clinical and biological factors associated with echocardiographic changes.
methodsOne hundred six patients (mean age 48 ± 16, 73% male) who underwent KT at the University Hospital of Nancy between 2007 and 2018 were retrospectively investigated. Pre- and post-KT echocardiography findings (8.6 months before and 22 months after KT on average, respectively) were centralised, blind-reviewed and compared.
resultsA majority of patients (60%) had either a left ventricular (LV) ejection fraction < 50%, at least moderately abnormal LV mass index or left atrial (LA) dilatation at pretransplanted echocardiography. After KT, LV remodelling and diastolic doppler indices did not significantly change whereas LA volume index (LAVI) increased (35.9 mL/m DISCUSSION/
conclusionAdverse remodelling of the left atrial volume occurred after KT, predominantly in patients with lower pre-KT blood calcium, poorer graft function and post-KT hypertension. These results suggest that a better management of modifiable factors such as pre-KT hyperparathyroidism or post-KT hypertension could limit post-KT cardiac remodelling.
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