Evidence map›Paper›PMID 37084120›Full record

ArticleGeroScience2023

cAMP signaling affects age-associated deterioration of pacemaker beating interval dynamics.

Sofia Segal, Ori Shemla, Rotem Shapira, Noa Kirschner Peretz, Yevgeniya Lukyanenko, Inbar Brosh, Joachim Behar, Edward G Lakatta, Kenta Tsutsui, Yael Yaniv

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Sofia Segal *Laboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel.
Ori Shemla *Laboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel.
Rotem ShapiraLaboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel.
Noa Kirschner PeretzLaboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel.
Yevgeniya LukyanenkoIntramural Research Program, National Institute On Aging, Baltimore, MD, USA.
Inbar BroshLaboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel.
Joachim BeharLaboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel.
Edward G LakattaIntramural Research Program, National Institute On Aging, Baltimore, MD, USA.
Kenta Tsutsui *Intramural Research Program, National Institute On Aging, Baltimore, MD, USA. knt22e@gmail.com.
Yael Yaniv *Laboratory of Bioelectric and Bioenegetic, The Faculty of Biomedical Engineering, Technion-IIT, Haifa, Israel. yaely@bm.technion.ac.il.
Technion – Israel Institute of Technology · ILInstitute on Aging · USNational Institute on Aging · USSaitama Medical University · JP

Funding

Israel Science Foundation 330/19
6 · The paper itself

Abstract

Sinoatrial node (SAN) beating interval variability (BIV) and the average beating interval (BI) are regulated by a coupled-clock system, driven by Ca

Indexed as

Pacemaker, ArtificialSignal TransductionAnimalsMiceSinoatrial NodeAgingBeating ratecAMPPacemaker

Identifiers

PMID37084120
PMCPMC10651572
OpenAlexW4366602443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.