Evidence map›Paper›PMID 37084104›Full record

Trial reportAIDS and behavior2023

An Intervention to Improve Mental Health and HIV Care Engagement Among Perinatal Women in Malawi: A Pilot Randomized Controlled Trial.

Angela M Bengtson, Teresa R Filipowicz, Steven Mphonda, Michael Udedi, Kazione Kulisewa, Samantha Meltzer-Brody, Bradley N Gaynes, Vivian F Go, Dixon Chibanda, Ruth Verhey and 2 more

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04143009 nacompletednot on this map

Adaptation of the Friendship Bench Mental Health Intervention for HIV-infected Perinatal Women in Lilongwe (Periscope)

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2019 to 2022Enrolled92ConditionsHuman Immunodeficiency Virus, Perinatal DepressionArmsEnhanced Friendship Bench, Enhanced Standard Care (Control), Adapted Friendship Bench
NCT06659315 narecruitingnot on this mapstarted 2025, after this paper: background citation

Addressing Perinatal Depression and PMTCT Adherence in Malawi: A Couple-Based Approach

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2027Enrolled180ConditionsHIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health, Depression During Pregnancy, PMTCTArmsCouples Problem Solving Therapy
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Angela M BengtsonDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA. angela_bengtson@brown.edu.
Teresa R FilipowiczDepartment of Epidemiology, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.
Steven MphondaUNC Project Malawi, Lilongwe, Malawi.
Michael UdediMental Health Unit, Malawi Ministry of Health, Lilongwe, Malawi.
Kazione KulisewaDepartment of Psychiatry and Mental Health, Kamuzu University of Health Sciences, Blantyre, Malawi.
Samantha Meltzer-BrodyDepartment of Psychiatry, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.
Bradley N GaynesDepartment of Epidemiology, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.
Vivian F GoDepartment of Health Behavior, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.
Dixon ChibandaDepartment of Psychiatry & Research Support Centre, University of Zimbabwe, Harare, Zimbabwe.
Ruth VerheyFriendship Bench Zimbabwe, Harare, Zimbabwe.
Mina C HosseinipourUNC Project Malawi, Lilongwe, Malawi.
Brian Wells PenceDepartment of Epidemiology, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USBrown University · USKamuzu Central Hospital · MWMinistry of Health · MWUniversity of Zimbabwe · ZW

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
Malawian Program for Mental Health Research Training (WARMHEART)D43TW011794 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRADLEY N GAYNES, Kazione Radson Kulisewa · 2020 to 2026
$1.8M
Adaptation of the Friendship Bench mental health intervention for HIV-infected perinatal women in MalawiR34MH116806 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENGTSON, ANGELA, PENCE, BRIAN W · 2018 to 2022
$761k
An Implementation Science Approach to Monitoring Engagement in HIV CareR00MH112413 · NIMH · BROWN UNIVERSITY · PI BENGTSON, ANGELA · 2019 to 2021
$747k
FIC NIH HHS D43 TW010060FIC NIH HHS D43 TW011794NIAID NIH HHS P30 AI050410NIMH NIH HHS R00 MH112413NIMH NIH HHS R00MH112413NIMH NIH HHS R34 MH116806NIMH NIH HHS R34MH116806
6 · The paper itself

Abstract

Perinatal depression (PND) is common and an important barrier to engagement in HIV care for women living with HIV (WLHIV). Accordingly, we adapted and enhanced The Friendship Bench, an evidence-based counseling intervention, for perinatal WLHIV. In a pilot randomized trial (NCT04143009), we evaluated the feasibility, acceptability, fidelity, and preliminary efficacy of the Enhanced Friendship Bench (EFB) intervention to improve PND and engagement in HIV care outcomes. Eighty pregnant WLHIV who screened positive for PND symptoms on the Self-Report Questionnaire (≥ 8) were enrolled, randomized 1:1 to EFB or usual care, and followed through 6 months postpartum. Overall, 100% of intervention participants were satisfied with the intervention and 93% found it beneficial to their overall health. Of 82 counseling sessions assessed for fidelity, 83% met or exceeded the fidelity threshold. At 6 months postpartum, intervention participants had improved depression remission (59% versus 36%, RD 23%, 95% CI 2%, 45%), retention in HIV care (82% versus 69%, RD 13%, -6%, 32%), and viral suppression (96% versus 90%, RD 7%, -7%, 20%) compared to usual care. Adverse events did not differ by arm. These results suggest that EFB intervention should be evaluated in a fully powered randomized trial to evaluate its efficacy to improve PND and engagement in HIV care outcomes for WLHIV.

Indexed as

HIV InfectionsDepressionFemaleHumansMalawiMental HealthPilot ProjectsPregnancyEngagement in HIV careHIVMalawiOption B+Perinatal depression

Identifiers

PMID37084104
PMCPMC10119837
OpenAlexW4366603437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.