Evidence map›Paper›PMID 37083346›Full record

ArticleACS applied materials & interfaces2023

Exploring Low-Power Single-Pulsed Laser-Triggered Two-Photon Photodynamic/Photothermal Combination Therapy Using a Gold Nanostar/Graphene Quantum Dot Nanohybrid.

Amir Soleimany, Sepideh Khoee, Sofia Dias, Bruno Sarmento

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Near-Infrared Driven Gold Nanoparticles-Decorated g-CInternational journal of nanomedicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amir Soleimanyi3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal.ORCID 0000-0002-6032-1565
Sepideh KhoeePolymer Laboratory, School of Chemistry, College of Science, University of Tehran, Tehran 14155-6455, Iran.
Sofia Diasi3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal.
Bruno Sarmentoi3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal.ORCID 0000-0001-5763-7553

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combined photodynamic/photothermal therapy (PDT/PTT) has emerged as a promising cancer treatment modality due to its potential synergistic effects and identical treatment procedures. However, its clinical application is hindered by long treatment times and complicated treatment operations when separate illumination sources are required. Here, we present the development of a new nanohybrid comprising thiolated chitosan-coated gold nanostars (AuNS-TCS) as the photothermal agent and riboflavin-conjugated N,S-doped graphene quantum dot (Rf-N,S-GQD) as the two-photon photosensitizer (TP-PS). The nanohybrid demonstrated combined TP-PDT/PTT when a low-power, single-pulsed laser irradiation was applied, and the localized surface plasmon resonance of AuNS was in resonance with the TP-absorption wavelength of Rf-N,S-GQD. The TCS coating significantly enhanced the colloidal stability of AuNSs while providing a suitable substrate to electrostatically anchor negatively charged Rf-N,S-GQDs. The plasmon-enhanced singlet oxygen (

Indexed as

GraphitePhotochemotherapyQuantum DotsGoldLasersPhotosensitizing AgentsGoldGraphitePhotosensitizing Agentshyperthermiaphototherapyplasmonic metalquantum dotssinglet oxygenthiolated chitosan

Identifiers

PMID37083346
PMCPMC10165604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.