ReviewThe World Allergy Organization journal2023
DRESS syndrome: A literature review and treatment algorithm.
Review in The World Allergy Organization journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.
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Who cites it
100 citing papers in PubMed.
- [Management of emergencies in rheumatology].Zeitschrift fur Rheumatologie · 2026Review
- A Rare Case of Minocycline-induced DIHS/DRESS with Predominant Pulmonary Involvement.Acta dermato-venereologica · 2026Article
- Combined immune modulation reveals carbamazepine-associated CD8Archives of toxicology · 2026Article
- Granulomatous Interstitial Nephritis With Perivascular Involvement in Carbamazepine-Induced DRESS Syndrome: A Case Report.Kidney medicine · 2026Article
- Beyond the drug: autoimmune predisposition to DRESS syndrome.Proceedings (Baylor University. Medical Center) · 2026Article
- New Insights Into Immunomodulatory Strategies for Drug Hypersensitivity Reactions: An EAACI Task Force Report.Clinical and translational allergy · 2026Review
- Allopurinol-Induced Leukocytoclastic Vasculitis With Systemic Inflammatory Response: A Case Report From Azerbaijan.Cureus · 2026Article
- [Erythroderma: etiology, diagnosis, and management-an overview].Dermatologie (Heidelberg, Germany) · 2026Review
- Hilar and Mediastinal Lymphadenopathy as a Potential Manifestation of Azathioprine-Associated Hypersensitivity Syndrome.Pharmaceuticals (Basel, Switzerland) · 2026Article
- [Management of emergencies in rheumatology].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Article
- DRESS'ed in Shock and Delay in Eosinophilia Resolution: Management Dilemmas in a Complex Case of Vancomycin-Induced DRESS Syndrome.The American journal of case reports · 2026Article
- Article
- Not all 'natural' is safe: A naturally occurring glucagon-like peptide-1 mimetic associated with drug-induced hypersensitivity syndrome.JAAD case reports · 2026Article
- Severe Toxicodermia due to Apalutamide: A Case Report of DRESS in an Elderly Adult.International journal of hematology-oncology and stem cell research · 2026Article
- A Narrative Review of Drug-Induced Haemophagocytic Lymphohistiocytosis: A Rare but Relevant Differential Diagnosis.International archives of allergy and immunology · 2026Review
- Review
- Antiepileptic Drug-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A Case Series.Cureus · 2026Article
- Article
- A Challenging Case of Trimethoprim-Sulfamethoxazole Associated Drug Reaction With Eosinophilia and Systemic Symptoms With Prominent Hepatic Involvement and an Atypical Rash.ACG case reports journal · 2026Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug reaction with eosinophilia and systemic symptoms, known by its acronym in English as DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms), clinically manifests with fever, facial edema, lymphadenopathy, a morbilliform rash, and organ involvement. Laboratory results reveal leukocytosis, atypical lymphocytes, eosinophilia, and alterations of liver and kidney function tests. The actual incidence of DRESS is unknown, because it may vary depending on the type of medication and the immune status of each patient; also, because many cases remain undiagnosed or untreated. The drugs most associated with DRESS include antiepileptics, antibiotics, antituberculosis, and non-steroidal anti-inflammatory agents (NSAIDs). Its diagnosis is sometimes made late and can become a challenge. The diagnostic criteria proposed by the international Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) help to establish the diagnosis through a score system based on clinical and laboratory findings. The first step to identify the culprit is a thorough clinical history that includes all suspects, emphasizing those most known to cause DRESS syndrome according to the context and the literature. A skin biopsy may also be helpful in the diagnostic process. Patch testing is the test of choice to search for the culprit in cases of DRESS. Regarding prognosis, the estimated mortality due to DRESS is 3.8%. The main causes of mortality include fulminant hepatitis and liver necrosis. Several indicators of poor prognosis have been identified and these include an eosinophil count above 6000 × 10
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