Evidence map›Paper›PMID 37082588›Full record

ArticleBBA advances2022

Structural diversity, bioactivity, and biosynthesis of phosphoglycolipid family antibiotics: Recent advances.

Bohdan Ostash, Roman Makitrynskyy, Oleksandr Yushchuk, Victor Fedorenko

Open access · goldAbstract read
In one paragraph

Article in BBA advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Bohdan OstashDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv 79005, Ukraine.
Roman MakitrynskyyInstitute of Pharmaceutical Sciences, Albert-Ludwigs University, 79104 Freiburg, Germany.
Oleksandr YushchukDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv 79005, Ukraine.
Victor FedorenkoDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv 79005, Ukraine.
Lviv University · UAUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moenomycins, such as moenomycin A, are phosphoglycolipid specialized metabolites produced by a number of actinobacterial species. They are among the most potent antibacterial compounds known to date, which drew numerous studies directed at various aspects of the chemistry and biology of moenomycins. In this review, we outline the advances in moenomycin research over the last decade. We focus on biological aspects, highlighting the contribution of the novel methods of genomics and molecular biology to the deciphering of the biosynthesis and activity of moenomycins. Specifically, we describe the structural diversity of moenomycins as well as the underlying genomic variations in moenomycin biosynthetic gene clusters. We also describe the most recent data on the mechanism of action and assembly of complicated phosphoglycolipid scaffold. We conclude with the description of the genetic control of moenomycin production by

Indexed as

Bacterial cell wallBiosynthetic gene clustersPeptidoglycan glycosyltransferasesPhosphoglycolipid antibioticsStreptomyces

Identifiers

PMID37082588
PMCPMC10074958
OpenAlexW4309633453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.