Evidence map›Paper›PMID 37082057›Full record

ArticleJournal of oral and maxillofacial pathology : JOMFP

Plasma cells in oral lesion: A clue to diagnosis or a diagnostic dilemma.

Harpreet Kaur, Deepika Mishra, Ajoy Roychoudhury, Ashu Seith Bhalla, Prashant P S Ramteke, Lalit Kumar

Abstract read
In one paragraph

Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Harpreet KaurDepartment of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Deepika MishraDepartment of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Ajoy RoychoudhuryDepartment of Oral and Maxillofacial Surgery, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Ashu Seith BhallaDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Prashant P S RamtekeDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Lalit KumarDepartment of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Plasma cells can just represent a part of host inflammatory response or form the cornerstone of diagnosis such as IgG4-related disease (IgG4RD) and plasma cell dyscrasias and sometimes create a diagnostic dilemma. The study aims to discuss a series of plasma cell lesions which we encountered in the oral cavity, discuss the diagnostic conundrum of plasma cell lesions. We also propose a working classification for their interpretation. Materials and Methods: All plasma cell lesions affecting the oral and maxillofacial region were retrieved from the archives of the Department of Oral and Maxillofacial Pathology. The cases were analyzed on the basis of histomorphology and immunohistochemical markers along with clinical, imaging and laboratory findings. Results: Thirteen (0.64%) of 2026 oral lesions were diagnosed with plasma cell lesions. Out of 13 cases, 9 were plasma cell gingivitis, 2 IgG4-RD, 1 plasma cell myeloma and 1 plasmablastic lymphoma. Representative case from each category is discussed along with one case of well-differentiated squamous cell carcinoma (WDSCC) masquerading as plasma cell dyscrasias. Conclusion: We discuss the practical difficulties faced during the diagnosis of these oral plasma cell entities along with a working classification and propose an efficient diagnostic scheme for the correct characterization of these lesions.

Indexed as

Diagnostic approachoral cavityplasma cell gingivitisplasma cell lesionsplasma cell myeloma

Identifiers

PMID37082057
PMCPMC10112081

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