ArticleFrontiers in public health2023
Age- and sex-specific associations between sarcopenia severity and poor cognitive function among community-dwelling older adults in Japan: The IRIDE Cohort Study.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Association between temporalis muscle thickness and functional outcomes in acute stroke: A meta-analysis and GRADE approach.The journal of nutrition, health & aging · 2025Pooled it
- The association of sarcopenia, possible sarcopenia and cognitive impairment: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Sarcopenia Severity and the Accumulation of Geriatric Syndromes Among Older Adults: A Cross-Sectional Study from Vietnam.Geriatrics (Basel, Switzerland) · 2026Article
- The proportion of moderate-to-vigorous-intensity physical activity to total volume of physical activity correlates with decreased risk of possible sarcopenia: A prospective cohort study.Journal of exercise science and fitness · 2025Article
- Article
- Sarcopenia and cognitive performance in hospitalized older adults: evidence of an association.Frontiers in dementia · 2025Article
- Physical activity intensity, frequency, duration, volume and the risk of possible sarcopenia in middle-aged and older adults.GeroScience · 2024Article
- Preoperative Sarcopenia Severity and Clinical Outcomes after Total Hip Arthroplasty.Nutrients · 2024Article
- The bidirectional associations between sarcopenia-related traits and cognitive performance.Scientific reports · 2024Article
- Prevalence and factors associated with sarcopenia among older adults in a post-acute hospital in Singapore.PloS one · 2024Article
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Authors and funding
12 authors at 1 institution in 1 country.
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Abstract
Introduction: This study examined whether the association between sarcopenia severity and cognitive function differed according to sex and age in community-dwelling older adults in Japan. Methods: This is a cross-sectional study of older adults (age ≥ 65 years) consisting of five regional cohorts integrated as the Integrated Research Initiative for Living Well with Dementia (IRIDE) Cohort Study. Sarcopenia severity was determined based on the Asian Working Group for Sarcopenia 2019, which assessed grip strength, walking speed, and skeletal muscle mass index. Poor cognitive function was defined as a Mini-Mental State Examination score of ≤ 23. Odds ratios (ORs) and 95% confidence intervals (CIs) for poor cognitive function were calculated by sex and age group (65-74 and ≥75 years) using binomial logistic regression models, which were adjusted for age, educational attainment, history of non-communicable diseases, smoking and drinking habits, living alone, frequency of going outdoors, exercise habits, and depressive symptom. Results: Of the 8,180 participants, 6,426 (1,157 men aged 65-74 and 1,063 men aged 75 or older; 2,281 women aged 65-74 and 1,925 women aged 75 or older) were analyzed. The prevalence ratio of sarcopenia and severe sarcopenia were 309 (13.9%) and 92 (4.1%) among men and 559 (13.3%) and 166 (3.7%) among women, respectively. A total of 127 (5.8%) men and 161 (3.9%) women had a poor cognitive function. Setting non-sarcopenia as a reference, the adjusted ORs (95% CI) of poor cognitive function were 2.20 (1.54, 3.15) for sarcopenia and 3.56 (2.20, 5.71) for severe sarcopenia. A similar trend was observed in analyses stratified by sex and age, with linear associations ( Discussion and conclusion: Sarcopenia severity was linearly associated with poor cognitive function in adults aged ≥ 65 years, with a stronger association in women compared with men.
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