ArticleJAMIA open2023
Natural language processing-driven state machines to extract social factors from unstructured clinical documentation.
Article in JAMIA open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Applications of Natural Language Processing and Large Language Models for Social Determinants of Health: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Improving Clinical Documentation with Artificial Intelligence: A Systematic Review.Perspectives in health information management · 2024Pooled it
- Gender and other diversity-related factors in psychiatric hospital care: protocol for the participatory mixed-methods PSY-DIVER study.BMC psychiatry · 2026Article
- Modeling Patients' Progression through Health-Related Social Needs.Applied clinical informatics · 2025Article
- Performance of 4 Methods to Assess Health-Related Social Needs.JAMA network open · 2025Article
- Integrating a risk prediction score in a clinical decision support to identify patients with health-related social needs in the emergency department.JAMIA open · 2025Article
- Social determinants of health extraction from clinical notes across institutions using large language models.NPJ digital medicine · 2025Article
- Article
- Large-scale identification of social and behavioral determinants of health from clinical notes: comparison of Latent Semantic Indexing and Generative Pretrained Transformer (GPT) models.BMC medical informatics and decision making · 2024Article
- Article
- Generalizability and portability of natural language processing system to extract individual social risk factors.International journal of medical informatics · 2023Article
- Connecting the use of innovative treatments and glucocorticoids with the multidisciplinary evaluation through rule-based natural-language processing: a real-world study on patients with rheumatoid arthritis, psoriatic arthritis, and psoriasis.Frontiers in medicine · 2023Article
- Unsupervised SapBERT-based bi-encoders for medical concept annotation of clinical narratives with SNOMED CT.Digital healthArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study sought to create natural language processing algorithms to extract the presence of social factors from clinical text in 3 areas: (1) housing, (2) financial, and (3) unemployment. For generalizability, finalized models were validated on data from a separate health system for generalizability. Materials and Methods: Notes from 2 healthcare systems, representing a variety of note types, were utilized. To train models, the study utilized n-grams to identify keywords and implemented natural language processing (NLP) state machines across all note types. Manual review was conducted to determine performance. Sampling was based on a set percentage of notes, based on the prevalence of social need. Models were optimized over multiple training and evaluation cycles. Performance metrics were calculated using positive predictive value (PPV), negative predictive value, sensitivity, and specificity. Results: PPV for housing rose from 0.71 to 0.95 over 3 training runs. PPV for financial rose from 0.83 to 0.89 over 2 training iterations, while PPV for unemployment rose from 0.78 to 0.88 over 3 iterations. The test data resulted in PPVs of 0.94, 0.97, and 0.95 for housing, financial, and unemployment, respectively. Final specificity scores were 0.95, 0.97, and 0.95 for housing, financial, and unemployment, respectively. Discussion: We developed 3 rule-based NLP algorithms, trained across health systems. While this is a less sophisticated approach, the algorithms demonstrated a high degree of generalizability, maintaining >0.85 across all predictive performance metrics. Conclusion: The rule-based NLP algorithms demonstrated consistent performance in identifying 3 social factors within clinical text. These methods may be a part of a strategy to measure social factors within an institution.
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Registered trials
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