Evidence map›Paper›PMID 37081922›Full record

ArticleFrontiers in nutrition2023

Supplementation of hyaluronic acid injections with vitamin D improve knee function by attenuating synovial fluid oxidative stress in osteoarthritis patients with vitamin D insufficiency.

Jianlin Shen, Xiaoning Lin, Yujin Lin, Jiecheng Xiao, Changfu Wu, Feng Zheng, Xianwei Wu, Haibin Lin, Guoli Chen, Huan Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jianlin ShenDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Xiaoning LinDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Yujin LinDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Jiecheng XiaoDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Changfu WuDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Feng ZhengDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Xianwei WuDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Haibin LinDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Guoli ChenDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Huan LiuDepartment of Orthopedics, Affiliated Hospital of Putian University, Putian, Fujian, China.
Putian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: There is still controversy about the effect of vitamin D supplementation on osteoarthritis (OA). The purpose of this study was to investigate the effects of vitamin D supplementation with Hyaluronic acid (HA) injection on OA. Methods: We investigated serum vitamin D levels and oxidative stress (OS) in synovial fluid from patients with OA who underwent total knee arthroplasty (grade IV, Results: The results showed that the levels of glutathione peroxidase (GSH-PX) ( Conclusion: We conclude that maintenance of vitamin D sufficiency may be beneficial for the treatment of OA by improving OS in synovial fluid.

Indexed as

hyaluronic acidosteoarthritisoxidative stresssynovial fluidvitamin D

Identifiers

PMID37081922
PMCPMC10112517
OpenAlexW4362566860

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.