Evidence map›Paper›PMID 37081905›Full record

ArticleJournal of asthma and allergy2023

Allergen Sensitization in Children in Weifang, China: Differences Between Monosensitization and Polysensitization.

Xiyan Zhang, Hui Chen, Shengnan Liu, Xijuan Wang, Beibei Guo, Jingjing Liu, Shaojie Feng, Fengxia Liu

Abstract read
In one paragraph

Article in Journal of asthma and allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Xiyan ZhangSchool of Clinical Medicine, Weifang Medical University, Weifang, People's Republic of China.ORCID 0000-0001-6602-3721
Hui ChenSchool of Clinical Medicine, Weifang Medical University, Weifang, People's Republic of China.
Shengnan LiuDepartment of Blood Transfusion, Affiliated Hospital of Weifang Medical University, Weifang, People's Republic of China.
Xijuan WangDepartment of Allergy, Weifang People's Hospital, Weifang, People's Republic of China.
Beibei GuoDepartment of Allergy, Weifang People's Hospital, Weifang, People's Republic of China.
Jingjing LiuDepartment of Allergy, Weifang People's Hospital, Weifang, People's Republic of China.
Shaojie FengDepartment of Allergy, Weifang People's Hospital, Weifang, People's Republic of China.
Fengxia LiuDepartment of Allergy, Weifang People's Hospital, Weifang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Children are the age group with the highest prevalence of allergy diseases. There is currently a lack of knowledge regarding monosensitization and polysensitization characteristics in children. In this study, we investigated the characteristics and differences between monosensitization and polysensitization in children in Weifang, eastern China. Objective: To demonstrate the basic features of monosensitization and polysensitization in children. To explore the inherent and clinical parameter differences between monosensitized and polysensitized children. Material and Methods: A total of 6030 individuals with a physician-determined need for allergy testing were tested for 15 common allergens, including 9 aeroallergens and 6 food allergens. A total of 938 allergen-positive children aged 1 month to 18 years were eventually included in this analysis. Complete blood count results from the same time as the allergen test were derived from the computerized medical records. Intrinsic features such as age, gender, sIgE, T-IgE, and clinical parameters such as eosinophil percentage, eosinophil count, basophil percentage, and basophil count were compared. Results: The results showed that dust mite-related allergens, mould-related allergens, and tree and grass pollen-related allergens were the most prevalent allergens among monosensitized children. Additionally, the results of the combined pattern of polysensitive childhood allergens indicate the most common two allergens that were present together included dust mites and mould-related allergens, dust mite and Artemisia pollens, and dust mite and Humulus scandens pollens. Polysensitization can result in higher sIgE, T-IgE and eosinophil levels. Conclusion: In conclusion, we provide a basic overview of allergens in monosensitized and polysensitized children. These findings provide new insight into the management of allergic diseases, particularly from the standpoint of polysensitization.

Indexed as

allergic diseasechildreneosinophilsmonosensitizationpolysensitizationT-IgE

Identifiers

PMID37081905
PMCPMC10112473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.