ArticleRadiation oncology (London, England)2023
Dose coverage and breath-hold analysis of breast cancer patients treated with surface-guided radiotherapy.
Article in Radiation oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Surface-guided deep-inspiration breath-hold radiotherapy for left-sided breast cancer: a systematic review and meta-analysis of dosimetric outcomes and image-verified setup accuracy.Frontiers in oncology · 2026Pooled it
- Surface-guided radiation therapy combined with real-time position management-guided deep inspiratory breath-hold radiotherapy for left breast cancer.BMC cancer · 2026Trial
- The Prospective SPOTLESS Trial: Setup Accuracy of Tattoo-Less Surface-Guided Breast Radiotherapy Including Regional Nodal Irradiation.Journal of clinical medicine · 2026Article
- Impact of variation in voluntary moderate deep inspiration breath hold on the 3D dose distribution in breast cancer radiotherapy.Technical innovations & patient support in radiation oncology · 2026Article
- [Analysis of setup errors and their correlation with clinical factors in image-guided radiotherapy for prostate cancer using different immobilization devices].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Impact of eFOV CT distortion on surface-guided radiotherapy registration: Phantom-based analysis.Journal of applied clinical medical physics · 2025Article
- Setup Accuracy and Efficiency of Real-Time Video Assistance for Surface-Guided Positioning in Radiation Therapy of Right-Sided Locoregional Breast Cancer.Advances in radiation oncology · 2025Article
- Validation of in vivo dose using EPID combined with fan-beam CT guidance in post-breast-conserving radiotherapy for early-stage breast cancer.BMC cancer · 2025Article
- Dosimetric benefit and clinical feasibility of deep inspiration breath-hold and volumetric modulated arc therapy-based postmastectomy radiotherapy for left-sided breast cancer.Scientific reports · 2024Article
- Modeling of artificial intelligence-based respiratory motion prediction in MRI-guided radiotherapy: a review.Radiation oncology (London, England) · 2024Review
- Interfractional variation in whole-breast VMAT irradiation: a dosimetric study with complementary SGRT and CBCT patient setup.Radiation oncology (London, England) · 2024Article
- Setup and intra-fractional motion measurements using surface scanning in head and neck cancer radiotherapy- A feasibility study.Physics and imaging in radiation oncology · 2024Article
- Surface-Guided Radiotherapy: Can We Move on from the Era of Three-Point Markers to the New Era of Thousands of Points?Bioengineering (Basel, Switzerland) · 2023Review
- Analysis of Surface Guidance Versus Laser Alignment for Precision Lung Cancer Particle Therapy.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurface-guided radiotherapy (SGRT) is used to ensure a reproducible patient set-up and for intra-fraction motion monitoring. The arm position of breast cancer patients is important, since this is related to the position of the surrounding lymph nodes. The aim of the study was to investigate the set-up accuracy of the arm of patients positioned using SGRT. Moreover, the actual delivered dose was investigated and an extensive breath-hold analysis was performed.
methods84 patients who received local or locoregional breast radiation therapy were positioned and monitored using SGRT. The accuracy of the arm position, represented by the clavicle position, was studied on the anterior-posterior kV-image. To investigate the effect of changes in anatomy and patient set-up, the actual delivered dose was calculated on cone-beam CT-scans (CBCT). A deformable registration of the CT to the CBCT was applied to deform the structures of the CT onto the CBCT. The minimum dose in percentage of the prescribed dose that was received by 98% of different CTV volumes (D98) was determined. An extensive breath-hold analysis was performed and definitions for relevant parameters were given.
resultsThe arm position of 77 out of 84 patients in total was successful, based on the clavicle rotation. The mean clavicle rotation was 0.4° (± 2.0°). For 89.8% of the patients who were irradiated on the whole-breast D98 was larger than 95% of the prescribed dose (D98 > 95%). D98 > 95% applied for 70.8% of the patients irradiated on the chest wall. Concerning the lymph node CTVs, D98 > 95% for at least 95% of the patients. The breath-hold analysis showed a mean residual setup error of - 0.015 (± 0.90), - 0.18 (± 0.82), - 0.58 (± 1.1) mm in vertical, lateral, and longitudinal direction, respectively. The reproducibility and stability of the breath-hold was good, with median 0.60 mm (95% confidence interval (CI) [0.66-0.71] mm) and 0.20 mm (95% CI 0.21-0.23] mm), respectively.
conclusionsUsing SGRT we were able to position breast cancer patients successfully, with focus on the arm position. The actual delivered dose calculated on the CBCT was adequate and no relation between clavicle rotation and actual delivered dose was found. Moreover, breath-hold analysis showed a good reproducibility and stability of the breath-hold. Trial registration CCMO register NL69214.028.19.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.