ArticleBMC psychiatry2023
Hypnotic prescription trends and patterns for the treatment of insomnia in Japan: analysis of a nationwide Japanese claims database.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Initial treatment choices for long-term remission of chronic insomnia disorder in adults: a systematic review and network meta-analysis.Psychiatry and clinical neurosciences · 2024Pooled it
- Orexin receptor antagonists in the treatment of insomnia associated with psychiatric disorders: a systematic review.Translational psychiatry · 2024Pooled it
- Development and pilot evaluation of an electronic trigger-based surveillance model for sedative-hypnotic drug misuse in a tertiary hospital.Scientific reports · 2026Article
- Long-Term Trends in Prescribing of Etizolam for Hypnotic Use in a Japanese University Hospital.Human psychopharmacology · 2026Article
- Article
- Diagnosis, treatment, and associated outcomes of later-life insomnia: a narrative review.Sleep · 2025Review
- Novel hypnotics use and hip fracture risk in middle-aged and older adults: A large, population-based cohort study in Japan.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Medical Professionals and Pharmacological Intervention for the Treatment of Insomnia: A Cross-Sectional Study.Sleep science (Sao Paulo, Brazil) · 2025Article
- Characteristics of psychiatric patients with nightmares after suvorexant administration: A retrospective study.Neuropsychopharmacology reports · 2025Article
- Article
- Orexin receptor antagonist increases fat oxidation and suppresses protein catabolism during sleep in humans.iScience · 2024Article
- Treatment strategies for insomnia in Japanese primary care physicians' practice: A Web-based questionnaire survey.BMC primary care · 2024Article
- The effect of education regarding treatment guidelines for schizophrenia and major depressive disorders on psychiatrists' hypnotic medication prescribing behavior: a multicenter study.BMC psychiatry · 2024Article
- Lemborexant-induced interstitial lung disease: A case report.Respirology case reports · 2024Article
- Association between polypharmacy and the long-term prescription of hypnotics in Japan: a retrospective cross-sectional study.Frontiers in psychiatry · 2024Article
- Factors Associated with Prescriptions for an Orexin Receptor Antagonist Among Japanese Patients with Insomnia: Analysis of a Nationwide Japanese Claims Database.Drugs - real world outcomes · 2023Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited consensus regarding the optimal treatment of insomnia. The recent introduction of orexin receptor antagonists (ORA) has increased the available treatment options. However, the prescribing patterns of hypnotics in Japan have not been comprehensively assessed. We performed analyses of a claims database to investigate the real-world use of hypnotics for treating insomnia in Japan.
methodsData were retrieved for outpatients (aged ≥ 20 to < 75 years old) prescribed ≥ 1 hypnotic for a diagnosis of insomnia between April 1
resultsWe analyzed data for 130,177 new and 91,215 long-term users (2010-2019). Most new users were prescribed one MOA per year (97.1%-97.9%). In 2010, GABA
conclusionPrescriptions for hypnotics among new and long-term users in Japan showed distinct patterns and trends. Further understanding of the treatment options for insomnia with accumulating evidence for the risk-benefit balance might be beneficial for physicians prescribing hypnotics in real-world settings.
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