Evidence map›Paper›PMID 37081308›Full record

ArticleMolecular biology reports2023

Transferable IncX3 plasmid harboring bla

Ann A Elshamy, Sarra E Saleh, Khaled M Aboshanab, Mohammad M Aboulwafa, Nadia A Hassouna

Open access · hybridAbstract read
In one paragraph

Article in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Role of Mobilome in Carbapenem Resistance.Antibiotics (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Molecular epidemiological analysis of blaAnnals of clinical microbiology and antimicrobials · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ann A ElshamyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, P.O. Box 11566, Cairo, 11566, Egypt.
Sarra E SalehDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, P.O. Box 11566, Cairo, 11566, Egypt.
Khaled M AboshanabDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, P.O. Box 11566, Cairo, 11566, Egypt. aboshanab2012@pharma.asu.edu.eg.ORCID http://orcid.org/0000-0002-7608-850X
Mohammad M AboulwafaDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, P.O. Box 11566, Cairo, 11566, Egypt.
Nadia A HassounaDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, P.O. Box 11566, Cairo, 11566, Egypt.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe dissemination of carbapenem resistance via carbapenemases, such as the metallo-β-lactamase NDM, among Enterobacterales poses a public health threat. The aim of this study was to characterize a plasmid carrying the bla METHODS AND

resultsThe recovered plasmid was transformed into competent E. coli DH5α which acquired phenotypic resistance to cefoxitin, ceftazidime, and ampicillin/sulbactam, and intermediate sensitivity to ceftriaxone and imipenem (a carbapenem). Whole plasmid sequencing was performed on the extracted plasmid using the DNBSEQ™ platform. The obtained forward and reverse reads were assembled into contigs using the PRINSEQ and PLACNETw web tools. The obtained contigs were uploaded to PlasmidFinder and ResFinder for in silico plasmid typing and detection of antimicrobial resistance genes, respectively. The final consensus sequence was obtained using the Staden Package software. The plasmid (pNDMKP37, NCBI accession OK623716.1) was typed as an IncX3 plasmid with a size of 46,160 bp and harbored the antibiotic resistance genes bla

conclusionsThis is Egypt's first report of a transmissible plasmid co-harboring bla

Indexed as

Drug Resistance, BacterialEscherichia coliKlebsiella pneumoniaeAnti-Bacterial Agentsbeta-LactamasesCarbapenemsMicrobial Sensitivity TestsPhenotypePlasmidsAnti-Bacterial Agentsbeta-lactamase NDM-1beta-LactamasesCarbapenemsAntimicrobial resistanceAPH(3’)-VICarbapenem resistanceCRENDMPlasmid

Identifiers

PMID37081308
PMCPMC10209314
OpenAlexW4366465741

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.