ArticleNature medicine2023
Simulation-based estimates and projections of global, regional and country-level maternal mortality by cause, 1990-2050.
Article in Nature medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Male involvement interventions influencing maternal reproductive health outcomes: a narrative synthesis using RE-AIM with implications for maternal mortality in Africa.Frontiers in health services · 2025Pooled it
- Impact of COVID-19 on Maternal Health Service Uptake and Perinatal Outcomes in Sub-Saharan Africa: A Systematic Review.International journal of environmental research and public health · 2024Pooled it
- Global landscape of maternal hemorrhage mortality: a 40-year analysis based on GBD 2021 study.Archives of gynecology and obstetrics · 2026Article
- Regional inequalities and temporal trends in maternal disorders across sub-Saharan Africa, 1990-2023: a systematic analysis of the global burden of disease 2023 data.Archives of public health = Archives belges de sante publique · 2026Article
- Enjoying the Free Menu? Discoursing the Barriers to Exclusive Breastfeeding for Improved Maternal and Child Health in Tanzania: A Review of Evidence.Health science reports · 2026Review
- Maternal-Fetal Ultrasouno Video Dataset for End-to-end Intrapartum Biometry and Multi-task Learning.Scientific data · 2026Article
- Artificial intelligence for predicting and preventing adverse pregnancy outcomes addressing bias and clinical translation.Frontiers in digital health · 2026Review
- Global, regional, and national levels of maternal mortality, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.BMC pregnancy and childbirth · 2025Article
- Global, regional, and national time trends in prevalence of metabolic dysfunction associated steatotic liver disease among women of reproductive age: an age-period-cohort analysis for the global Burden of Disease 2021 study.Annals of medicine · 2025Article
- Maternal mortality ratios in Southeast Asia (1990-2021): trends, disparities, and projections through 2050 based on the global burden of disease 2021, with reference to SDG 3.1.BMC pregnancy and childbirth · 2025Article
- Global, regional, and national burden of maternal hemorrhage: a systematic analysis from the global burden of disease 2021 and projections to 2030.BMC pregnancy and childbirth · 2025Article
- Assessing differences in country-level estimates of maternal mortality: a comparison of GMatH, UN, and GBD model results for 2020.EClinicalMedicine · 2025Article
- The association between china's primary health care reform and inequalities in primary care utilisation and maternal mortality: a quasi-experimental longitudinal study from 2010 to 2019.International journal for equity in health · 2025Article
- Global, Regional, and National Trends in Maternal Mortality Ratio Across 37 High Income Countries From 1990 to 2021, With Projections up to 2050: A Comprehensive Analysis From the WHO Mortality Database.Journal of Korean medical science · 2025Article
- Assessment of healthcare facilities' readiness to provide antenatal care in Ethiopia: facility based study using service provision assessment data.Archives of public health = Archives belges de sante publique · 2025Article
- Article
- Maternal and child health services during the COVID-19 pandemic in India: an interrupted time-series analysis.Frontiers in global women's health · 2025Article
- Global maternal mortality projections by urban/rural location and education level: a simulation-based analysis.EClinicalMedicine · 2024Article
- A novel low-cost uterine balloon tamponade kit to tackle maternal mortality in low-resource settings.Scientific reports · 2024Article
- Global maternal health country typologies: A framework to guide policy.PLOS global public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal mortality is a major global health challenge. Although progress has been made globally in reducing maternal deaths, measurement remains challenging given the many causes and frequent underreporting of maternal deaths. We developed the Global Maternal Health microsimulation model for women in 200 countries and territories, accounting for individual fertility preferences and clinical histories. Demographic, epidemiologic, clinical and health system data were synthesized from multiple sources, including the medical literature, Civil Registration Vital Statistics systems and Demographic and Health Survey data. We calibrated the model to empirical data from 1990 to 2015 and assessed the predictive accuracy of our model using indicators from 2016 to 2020. We projected maternal health indicators from 1990 to 2050 for each country and estimate that between 1990 and 2020 annual global maternal deaths declined by over 40% from 587,500 (95% uncertainty intervals (UI) 520,600-714,000) to 337,600 (95% UI 307,900-364,100), and are projected to decrease to 327,400 (95% UI 287,800-360,700) in 2030 and 320,200 (95% UI 267,100-374,600) in 2050. The global maternal mortality ratio is projected to decline to 167 (95% UI 142-188) in 2030, with 58 countries above 140, suggesting that on current trends, maternal mortality Sustainable Development Goal targets are unlikely to be met. Building on the development of our structural model, future research can identify context-specific policy interventions that could allow countries to accelerate reductions in maternal deaths.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.