Evidence map›Paper›PMID 37080956›Full record

ArticleNature communications2023

Interstitial lung disease diagnosis and prognosis using an AI system integrating longitudinal data.

Xueyan Mei, Zelong Liu, Ayushi Singh, Marcia Lange, Priyanka Boddu, Jingqi Q X Gong, Justine Lee, Cody DeMarco, Chendi Cao, Samantha Platt and 12 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. A systematic review of the role of quantitative CT in the prognostication and disease monitoring of interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Contemporary management of sarcoidosis.Frontiers in medicine · 2026
    Review
  16. Review
  17. Review
  18. Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Xueyan MeiBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. xueyan.mei@icahn.mssm.edu.ORCID 0000-0001-7224-7318
Zelong LiuBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-6968-6467
Ayushi SinghDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Marcia LangeIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-2700-2279
Priyanka BodduIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Jingqi Q X GongDepartment of Pharmaceutical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Justine LeeDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Cody DeMarcoDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Chendi CaoBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samantha PlattIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-4637-8370
Ganesh SivakumarIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Benjamin GrossIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Mingqian HuangDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Joy MasseauxDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sakshi DuaDepartment of Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Adam BernheimDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Michael ChungDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-0976-4088
Timothy DeyerDepartment of Radiology, Cornell Medicine, New York, NY, USA.
Adam JacobiDepartment of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Maria PadillaDepartment of Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zahi A FayadBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. zahi.fayad@mssm.edu.ORCID 0000-0002-3439-7347
Yang YangBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. yang.yang4@ucsf.edu.ORCID 0000-0002-2841-4243
Icahn School of Medicine at Mount Sinai · USCornell University · USUniversity of California, San Francisco · US

Funding

J: NRSA Training CoreTL1TR004420 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI JANICE L GABRILOVE, Robert O Wright · 2022 to 2026
$3.9M
NCATS NIH HHS TL1 TR004420
6 · The paper itself

Abstract

For accurate diagnosis of interstitial lung disease (ILD), a consensus of radiologic, pathological, and clinical findings is vital. Management of ILD also requires thorough follow-up with computed tomography (CT) studies and lung function tests to assess disease progression, severity, and response to treatment. However, accurate classification of ILD subtypes can be challenging, especially for those not accustomed to reading chest CTs regularly. Dynamic models to predict patient survival rates based on longitudinal data are challenging to create due to disease complexity, variation, and irregular visit intervals. Here, we utilize RadImageNet pretrained models to diagnose five types of ILD with multimodal data and a transformer model to determine a patient's 3-year survival rate. When clinical history and associated CT scans are available, the proposed deep learning system can help clinicians diagnose and classify ILD patients and, importantly, dynamically predict disease progression and prognosis.

Indexed as

Lung Diseases, InterstitialDisease ProgressionHumansLungRetrospective StudiesThoraxTomography, X-Ray Computed

Identifiers

PMID37080956
PMCPMC10119160
OpenAlexW4366549962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.