Evidence map›Paper›PMID 37080724›Full record

ArticleAJNR. American journal of neuroradiology2023

Brain Activation Evoked by Motor Imagery in Pediatric Patients with Complete Spinal Cord Injury.

L Wang, W M Zheng, T F Liang, Y H Yang, B N Yang, X Chen, Q Chen, X J Li, J Lu, B W Li and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

L WangFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-0545-2308
W M ZhengFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-3410-6773
T F LiangDepartment of Medical Imaging (T.F.L., B.W.L.), Affiliated Hospital of Hebei Engineering University, Handan, Hebei Province, China.ORCID 0000-0002-0781-001X
Y H YangFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-3873-2106
B N YangFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-2306-9612
X ChenFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0036-6251
Q ChenDepartment of Radiology (Q.C.), Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-5210-9647
X J LiDepartment of Radiology (X.J.L.), China Rehabilitation Research Center, Beijing, China.ORCID 0000-0003-4614-5646
J LuFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-5274-8035
B W LiDepartment of Medical Imaging (T.F.L., B.W.L.), Affiliated Hospital of Hebei Engineering University, Handan, Hebei Province, China.ORCID 0000-0002-5831-0816
N ChenFrom the Department of Radiology and Nuclear Medicine (L.W., W.M.Z., Y.H.Y., B.N.Y., X.C., J.L., N.C.), Xuanwu Hospital, Capital Medical University, Beijing, China chenzen8057@sina.com.ORCID 0000-0002-0822-125X
Capital Medical University · CNHebei University of Engineering · CNChina Rehabilitation Research Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCurrently, there is no effective treatment for pediatric patients with complete spinal cord injury. Motor imagery has been proposed as an alternative to physical training for patients who are unable to move voluntarily. Our aim was to reveal the potential mechanism of motor imagery in the rehabilitation of pediatric complete spinal cord injury. MATERIALS AND

methodsTwenty-six pediatric patients with complete spinal cord injury and 26 age- and sex-matched healthy children as healthy controls were recruited. All participants underwent the motor imagery task-related fMRI scans, and additional motor execution scans were performed only on healthy controls. First, we compared the brain-activation patterns between motor imagery and motor execution in healthy controls. Then, we compared the brain activation of motor imagery between the 2 groups and compared the brain activation of motor imagery in pediatric patients with complete spinal cord injury and that of motor execution in healthy controls.

resultsIn healthy controls, compared with motor execution, motor imagery showed increased activation in the left inferior parietal lobule and decreased activation in the left supplementary motor area, paracentral lobule, middle cingulate cortex, and right insula. In addition, our results revealed that the 2 groups both activated the bilateral supplementary motor area, middle cingulate cortex and left inferior parietal lobule, and supramarginal gyrus during motor imagery. Compared with healthy controls, higher activation in the bilateral paracentral lobule, supplementary motor area, putamen, and cerebellar lobules III-V was detected in pediatric complete spinal cord injury during motor imagery, and the activation of these regions was even higher than that of healthy controls during motor execution.

conclusionsOur study demonstrated that part of the motor imagery network was functionally preserved in pediatric complete spinal cord injury and could be activated through motor imagery. In addition, higher-level activation in sensorimotor-related regions was also found in pediatric complete spinal cord injury during motor imagery. Our findings may provide a theoretic basis for the application of motor imagery training in pediatric complete spinal cord injury.

Indexed as

BrainSpinal Cord InjuriesBrain MappingChildHumansMagnetic Resonance Imaging

Identifiers

PMID37080724
PMCPMC10171374
OpenAlexW4366590982

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.