Evidence map›Paper›PMID 37080518›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2023

Nickel nanoparticles induce autophagy and apoptosis via HIF-1α/mTOR signaling in human bronchial epithelial cells.

Jiali Yuan, Yiqun Mo, Yue Zhang, Yuanbao Zhang, Qunwei Zhang

Open access · greenAbstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Inhalation exposure-induced toxicity and disease mediated via mTOR dysregulation.Experimental biology and medicine (Maywood, N.J.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jiali YuanDepartment of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, 40202, USA.
Yiqun MoDepartment of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, 40202, USA.
Yue ZhangNorthwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Yuanbao ZhangDepartment of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, 40202, USA.
Qunwei ZhangDepartment of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, 40202, USA. Electronic address: Qunwei.Zhang@louisville.edu.
University of Louisville · USNorthwestern University · US

Funding

University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
Mechanisms underlying metal nanoparticle-induced lung injury and fibrosisR01HL147856 · NHLBI · UNIVERSITY OF LOUISVILLE · PI ZHANG, QUNWEI · 2019 to 2022
$1.6M
The role of microRNA miR-21 in nickel nanoparticles-induced MMPs productionR15ES023693 · NIEHS · UNIVERSITY OF LOUISVILLE · PI ZHANG, QUNWEI · 2014 to 2014
$450k
Mechanisms of carcinogenic effects of nickel nanoparticlesR21ES028911 · NIEHS · UNIVERSITY OF LOUISVILLE · PI ZHANG, QUNWEI · 2018 to 2019
$424k
NHLBI NIH HHS R01 HL147856NIEHS NIH HHS P30 ES030283NIEHS NIH HHS R15 ES023693NIEHS NIH HHS R21 ES028911
6 · The paper itself

Abstract

With the rapid development of nanotechnology, the potential adverse health effects of nanoparticles have been caught more attention and become global concerns. However, the underlying mechanisms in metal nanoparticle-induced toxic effects are still largely obscure. In this study, we investigated whether exposure to nickel nanoparticles (Nano-Ni) and titanium dioxide nanoparticles (Nano-TiO

Indexed as

Metal NanoparticlesNickelApoptosisAutophagyEpithelial CellsHumansTOR Serine-Threonine KinasesMTOR protein, humanNickelTOR Serine-Threonine KinasesApoptosisAutophagyHIF-1αmTORNickel nanoparticles

Identifiers

PMID37080518
PMCPMC10231338
OpenAlexW4366262821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.