Evidence map›Paper›PMID 37080246›Full record

ArticleJournal of the American Medical Directors Association2023

Post-Acute Care Setting After Hip Fracture Hospitalization and Subsequent Opioid Use in Older Adults.

Meghan A Cupp, Francesca L Beaudoin, Kaleen N Hayes, Melissa R Riester, Sarah D Berry, Richa Joshi, Andrew R Zullo

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Meghan A CuppDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA; Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA. Electronic address: meghan_cupp@brown.edu.
Francesca L BeaudoinDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA; Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Kaleen N HayesDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Melissa R RiesterDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Sarah D BerryDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Richa JoshiDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Andrew R ZulloDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA; Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA; Center of Innovation in Long-Term Services and Supports, Providence Veterans Affairs Medical Center, Providence, RI, USA; Department of Pharmacy, Rhode Island Hospital, Providence, RI, USA.
Brown University · USBeth Israel Deaconess Medical Center · USProvidence College · US

Funding

Clinically Significant Drug Interactions among Nursing Home Residents with ADRDR01AG077620 · NIA · BROWN UNIVERSITY · PI Andrew Reis Zullo · 2022 to 2026
$3.5M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Opioid use in post-acute hip fracture care: prescribing patterns, effectiveness, and safetyR21AG061632 · NIA · BROWN UNIVERSITY · PI BEAUDOIN, FRANCESCA, ZULLO, ANDREW REIS · 2019 to 2020
$462k
NIA NIH HHS R01 AG065722NIA NIH HHS R01 AG077620NIA NIH HHS R21 AG061632
6 · The paper itself

Abstract

objectivePain management in post-acute care (PAC) requires careful balance, with both opioid use and inadequate pain treatment linked to poor outcomes. We describe opioid use among older adults following discharge from PAC for hip fracture in skilled nursing facilities (SNFs) and inpatient rehabilitation facilities (IRFs).

designRetrospective cohort. SETTING AND

participantsMedicare beneficiaries with Medicare Provider Analysis (MedPAR) claims, aged 66 years and older with a hip fracture hospitalization between 2012 and 2018 followed by PAC in SNFs or IRFs and then discharge to the community.

methodsIndividuals were followed from PAC discharge for up to 1 year to assess opioid use. Covariate-standardized risk ratios (RR) and risk differences (RD) for opioid use within 7 days of PAC discharge were estimated via parametric g-formula with modified Poisson regression, and hazard ratios (HRs) for any post-PAC opioid use and long-term opioid use via Fine-Gray sub-distribution hazards regression.

resultsOf 101,021 individuals, 80% (n = 80,495) were discharged from SNFs and 20% (n = 20,526) from IRFs. Opioids were dispensed to 50,433 patients (50%) overall and the 1-year cumulative incidence was notably higher in IRF (68%) than SNF (46%) patients. The adjusted risk of discharge from PAC with an opioid was 41% lower after SNFs versus IRFs [RR: 0.59; 95% confidence limits (CLs): 0.57-0.61; and RD: -0.16; 95% CLs: -0.17 to -0.15]. The adjusted rate of any opioid use in the year after PAC discharge was 44% lower (HR: 0.56; 95% CLs: 0.54-0.57) and of long-term opioid use was 17% lower (HR: 0.83; 95% CLs: 0.80-0.87) after SNFs versus IRFs. CONCLUSIONS AND IMPLICATIONS: Opioid use is highly prevalent upon discharge from PAC after hip fracture, with lower use after SNF versus IRF care. Future research should assess the benefits and harms of post-PAC opioid prescribing and whether care practices during PAC can be improved to optimize long-term opioid use.

Indexed as

Analgesics, OpioidHip FracturesAgedHospitalizationHumansMedicarePractice Patterns, Physicians'Retrospective StudiesSubacute CareUnited StatesAnalgesics, Opioidaccidental fallsanalgesicsgeriatricship fracturesopioidSkilled nursing facilities

Identifiers

PMID37080246
PMCPMC10293035
OpenAlexW4366144785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.