Evidence map›Paper›PMID 37079138›Full record

ArticleLangenbeck's archives of surgery2023

18F-fluorocholine PET/MRI versus ultrasound and sestamibi for the localization of parathyroid adenomas.

M E Noltes, L Rotstein, A Eskander, W P Kluijfhout, P Bongers, A H Brouwers, S Kruijff, U Metser, J D Pasternak, P Veit-Haibach

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Challenges and unmet needs of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. MR Pulse Sequences for Parathyroid Adenoma Imaging Using [Nuclear medicine and molecular imaging · 2026
    Article
  3. [European journal of nuclear medicine and molecular imaging · 2025
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

M E NoltesUniversity of Groningen, University Medical Center Groningen, Department of Surgery, Groningen, the Netherlands.
L RotsteinSection of Endocrine Surgery, Division of General Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.
A EskanderDepartment of Otolaryngology-Head and Neck Surgery, Michael Garron Hospital, University of Toronto, Toronto, Ontario, Canada.
W P KluijfhoutSection of Endocrine Surgery, Division of General Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.
P BongersUniversity of Groningen, University Medical Center Groningen, Department of Surgery, Groningen, the Netherlands.
A H BrouwersUniversity of Groningen, University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen, the Netherlands.
S KruijffUniversity of Groningen, University Medical Center Groningen, Department of Surgery, Groningen, the Netherlands.
U MetserToronto Joint Department Medical Imaging, University Health Network, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
J D Pasternak *Section of Endocrine Surgery, Division of General Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada. jesse.pasternak@uhn.ca.
P Veit-Haibach *Toronto Joint Department Medical Imaging, University Health Network, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
University of Toronto · CAUniversity Health Network · CAToronto East General Hospital · CAUniversity Medical Center Groningen · NLUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccurate preoperative localization is imperative to facilitate a minimally invasive parathyroidectomy (MIP) in primary hyperparathyroidism (pHPT). This study aims to compare the diagnostic value of standard-of-care localization techniques (ultrasound [US] and

methodsWe conducted a prospective, appropriately powered, study to compare the diagnostic value of -FCH PET/MRI to that of the US and

resultsForty-one patients underwent FCH-PET/MRI of which 36 patients had parathyroidectomy. In these 36 patients, 41 parathyroid lesions were histologically confirmed as adenomas or hyperplastic glands. Per-lesion sensitivity of FCH-PET/MRI was 82.9% and of US and

conclusionsFCH-PET/MRI is a highly accurate imaging modality for localization of parathyroid adenomas in a tertiary center in North America. It is a superior functional imaging modality to

Indexed as

Hyperparathyroidism, PrimaryParathyroid NeoplasmsCanadaCholineHumansMagnetic Resonance ImagingOrganotechnetium CompoundsParathyroid GlandsPositron-Emission TomographyProspective StudiesRadiopharmaceuticalsTechnetium Tc 99m SestamibiCholinefluorocholinefluoromethylcholineOrganotechnetium CompoundsRadiopharmaceuticalsTechnetium Tc 99m Sestamibi[F-18]-fluorocholine PETMagnetic resonance imagingNuclear imagingParathyoidectomyParathyroidPrimary hyperparathyroidism

Identifiers

PMID37079138
OpenAlexW4366462999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.