Evidence map›Paper›PMID 37079065›Full record

ArticleCancer immunology, immunotherapy : CII2023

Massively recruited sTLR9

Mengyuan Kou, Wenting Lu, Mengru Zhu, Kuo Qu, Liying Wang, Yongli Yu

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mengyuan KouDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Wenting LuDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Mengru ZhuDepartment of Developmental-Behavioral Pediatrics, The First Hospital of Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Kuo QuDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Liying WangDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, People's Republic of China. wangliy@jlu.edu.cn.
Yongli YuDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin, People's Republic of China. ylyu@jlu.edu.cn.
Jilin University · CN

Funding

National Natural Science Foundation of China 31670937
6 · The paper itself

Abstract

Neutrophils exert either pro- or anti-tumor activities. However, few studies have focused on neutrophils at the tumor initiation stage. In this study, we unexpectedly found a subcutaneous nodule in the groin areas of mice inoculated with tumor cells. The nodule was developed 24 h after the inoculation, filled with tumor cells and massively recruited neutrophils, being designated as tumor nodules. 22% of the neutrophils in tumor nodules are surface TLR9 (sTLR9) expressing neutrophils (sTLR9

Indexed as

NeutrophilsToll-Like Receptor 9AnimalsMiceToll-Like Receptor 9NeutrophilsSubcutaneous noduleSurface Toll-like receptor 9Tumor cell inoculationTumor development

Identifiers

PMID37079065
PMCPMC10992372
OpenAlexW4366463929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.