Evidence map›Paper›PMID 37078969›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2023

Goal-Focused Emotion-Regulation Therapy (GET) in Young Adult Testicular Cancer Survivors: A Randomized Pilot Study.

Michael A Hoyt, Ashley Wei-Ting Wang, Raymond Carrillo Ceja, Jennifer S Cheavens, Michael A Daneshvar, Darren R Feldman, Samuel A Funt, Christian J Nelson

Erratum issued Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04150848 (A Biobehavioral Intervention for Young Men With Testicular Cancer), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04150848 phase2unknown statusnot on this map

A Biobehavioral Intervention for Young Men With Testicular Cancer: A Pilot Study

TypeinterventionalSponsorUniversity of California, IrvineRan2018 to 2021Enrolled100ConditionsTestis CancerArmsGoal-Focused Emotion Regulation Therapy (GET), Individual Supportive Psychotherapy (ISP)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Young adult Latino testicular cancer survivors: a pilot study of Goal-focused Emotion regulation Therapy (GET).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Michael A HoytDepartment of Population Health & Disease Prevention, University of California, Irvine, Irvine, CA, USA.ORCID 0000-0003-2274-1902
Ashley Wei-Ting WangDepartment of Psychology, Soochow University, Suzhou, Taiwan.
Raymond Carrillo CejaDepartment of Population Health & Disease Prevention, University of California, Irvine, Irvine, CA, USA.
Jennifer S CheavensDepartment of Psychology, Ohio State University, Columbus, OH, USA.
Michael A DaneshvarDepartment of Urology, University of California, Irvine, Irvine, CA, USA.
Darren R FeldmanDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Samuel A FuntDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Christian J NelsonDepartment of Psychiatry and Behavioral Science, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NCATS NIH HHS UL1 TR000457NCATS NIH HHS UL1TR000457NCATS NIH HHS UL1 TR001414NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA062203NIH HHS P30CA062203
6 · The paper itself

Abstract

backgroundYoung adult testicular cancer survivors experience adverse impacts after treatment. We developed Goal-focused Emotion-regulation Therapy (GET) to improve distress symptoms, emotion regulation, and goal navigation skills. PURPOSE: This pilot study examined GET versus an active control intervention in young adult survivors of testicular cancer.

methodsSeventy-five eligible survivors treated with chemotherapy were randomized to receive GET or Individual Supportive Listening (ISL). Study acceptability, engagement, and tolerability were examined, and intervention fidelity and therapeutic alliance were compared between arms. Preliminary efficacy was evaluated by effect sizes for between-group changes in primary (anxiety and depressive symptoms) and secondary (career confusion, goal navigation, and emotion regulation) outcomes from baseline to immediately and 3-month post-intervention.

resultsAmong the 38 men randomized to GET, 81.1% completed all study sessions compared with 82.4% of the 37 men assigned to ISL. Fidelity to the intervention was 87% in GET. Therapeutic alliance wassignificantly higher among those receiving GET versus ISL. Participants exhibited a medium group-by-time effect size with greater reductions in depressive (d = 0.45) and anxiety (d = 0.29) symptoms for those in GET versus ISL, with a similar pattern at 3 months for depressive (d = 0.46) and anxiety (d = 0.46) symptoms.

conclusionsGET is a feasible and acceptable intervention for reducing adverse outcomes after testicular cancer for young adults. Observed effect sizes preliminarily suggest meaningful change, though should be interpreted with caution in small samples. GET may be a developmentally-matched behavioral approach to improve psychosocial function in this cancer group. CLINICAL TRIAL INFORMATION: Clinicaltrials.gov, NCT04150848. Registered on October 28, 2019.

Indexed as

Emotional RegulationTesticular NeoplasmsGoalsHumansMaleNeoplasms, Germ Cell and EmbryonalPilot ProjectsSurvivorsYoung AdultBiobehavioralEmotion regulationPsycho-oncologySurvivorshipTesticular cancerYoung adults

Identifiers

PMID37078969
PMCPMC10441857

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.