Evidence map›Paper›PMID 37078061›Full record

ArticleMolecular therapy. Nucleic acids2023

Partial restoration of brain dystrophin by tricyclo-DNA antisense oligonucleotides alleviates emotional deficits in

Amel Saoudi, Sacha Barberat, Olivier le Coz, Ophélie Vacca, Mathilde Doisy Caquant, Thomas Tensorer, Eric Sliwinski, Luis Garcia, Francesco Muntoni, Cyrille Vaillend and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Dystrophin rescue in the brain for DMD.Molecular therapy. Nucleic acids · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Behavioral improvement in dystrophicMolecular therapy. Nucleic acids · 2025
    Article
  9. Article
  10. Review
  11. Clinical applications of exon-skipping antisense oligonucleotides in neuromuscular diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Networking to OptimizeBiomedicines · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Amel SaoudiUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Sacha BarberatUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Olivier le CozUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Ophélie VaccaUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Mathilde Doisy CaquantUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Thomas TensorerSQY Therapeutics - Synthena, UVSQ, 78180 Montigny le Bretonneux, France.
Eric SliwinskiSQY Therapeutics - Synthena, UVSQ, 78180 Montigny le Bretonneux, France.
Luis GarciaUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Francesco MuntoniThe Dubowitz Neuromuscular Centre, Developmental Neurosciences Research and Teaching Department, Great Ormond Street Institute of Child Health, University College London, WC1N 1EH London, UK.
Cyrille VaillendUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, 91400 Saclay, France.
Aurélie GoyenvalleUniversité Paris-Saclay, UVSQ, Inserm, END-ICAP, 78000 Versailles, France.
Inserm · FRCentre National de la Recherche Scientifique · FRUniversité de Versailles Saint-Quentin-en-Yvelines · FRInstitute of Child Health · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

antisense oligonucleotidesbrain comorbiditiesCNS deliveryDuchenne muscular dystrophyexon-skippingMT: Oligonucleotides: Therapies and Applications

Identifiers

PMID37078061
PMCPMC10106732
OpenAlexW4328108212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.