Evidence map›Paper›PMID 37078053›Full record

ArticleBiomedical optics express2023

3D stimulated Raman spectral imaging of water dynamics associated with pectin-glycocalyceal entanglement.

Moritz Floess, Tobias Steinle, Florian Werner, Yunshan Wang, Willi L Wagner, Verena Steinle, Betty S Liu, Yifan Zheng, Zi Chen, Maximilian Ackermann and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Biomechanics of a Plant-Derived Sealant for Corneal Injuries.Translational vision science & technology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Moritz Floess4 Physics Institute and Stuttgart Research Center of Photonic Engineering, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany.ORCID https://orcid.org/0000-0002-0474-5291
Tobias Steinle4 Physics Institute and Stuttgart Research Center of Photonic Engineering, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany.
Florian Werner4 Physics Institute and Stuttgart Research Center of Photonic Engineering, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany.
Yunshan Wang4 Physics Institute and Stuttgart Research Center of Photonic Engineering, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany.
Willi L WagnerDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany.
Verena SteinleDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany.
Betty S LiuLaboratory of Adaptive and Regenerative Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Yifan ZhengLaboratory of Adaptive and Regenerative Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Zi ChenLaboratory of Adaptive and Regenerative Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Maximilian AckermannInstitute of Pathology and Department of Molecular Pathology, Helios University Clinic Wuppertal, University of Witten-Herdecke, Wuppertal, Germany.
Steven J MentzerLaboratory of Adaptive and Regenerative Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Harald Giessen4 Physics Institute and Stuttgart Research Center of Photonic Engineering, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany.ORCID https://orcid.org/0000-0002-4270-3850

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pectin is a heteropolysaccharide responsible for the structural integrity of the cell walls of terrestrial plants. When applied to the surface of mammalian visceral organs, pectin films form a strong physical bond with the surface glycocalyx. A potential mechanism of pectin adhesion to the glycocalyx is the water-dependent entanglement of pectin polysaccharide chains with the glycocalyx. A better understanding of such fundamental mechanisms regarding the water transport dynamics in pectin hydrogels is of importance for medical applications, e.g., surgical wound sealing. We report on the water transport dynamics in hydrating glass-phase pectin films with particular emphasis on the water content at the pectin-glycocalyceal interface. We used label-free 3D stimulated Raman scattering (SRS) spectral imaging to provide insights into the pectin-tissue adhesive interface without the confounding effects of sample fixation, dehydration, shrinkage, or staining.

Identifiers

PMID37078053
PMCPMC10110326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.