Evidence map›Paper›PMID 37078047›Full record

ArticleBiomedical optics express2023

Fusion deep learning approach combining diffuse optical tomography and ultrasound for improving breast cancer classification.

Menghao Zhang, Minghao Xue, Shuying Li, Yun Zou, Quing Zhu

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Convolutional-transformer fusion of ultrasound and diffuse optical tomography for breast lesion classification.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Menghao ZhangElectrical and System Engineering Department, Washington University in St. Louis, 1 Brooking Dr, St. Louis, MO 63130, USA.
Minghao XueBiomedical Engineering Department, Washington University in St. Louis, 1 Brooking Dr, St. Louis, MO 63130, USA.
Shuying LiBiomedical Engineering Department, Washington University in St. Louis, 1 Brooking Dr, St. Louis, MO 63130, USA.
Yun ZouBiomedical Engineering Department, Washington University in St. Louis, 1 Brooking Dr, St. Louis, MO 63130, USA.
Quing ZhuElectrical and System Engineering Department, Washington University in St. Louis, 1 Brooking Dr, St. Louis, MO 63130, USA.ORCID https://orcid.org/0000-0002-1837-2588
Washington University in St. Louis · US

Funding

Improving diagnostic US for reduction of benign breast biopsies using US-guided Optical TomographyR01CA228047 · NCI · WASHINGTON UNIVERSITY · PI POPLACK, STEVEN, ZHU, QUING · 2019 to 2023
$1.9M
NCI NIH HHS R01 CA228047
6 · The paper itself

Abstract

Diffuse optical tomography (DOT) is a promising technique that provides functional information related to tumor angiogenesis. However, reconstructing the DOT function map of a breast lesion is an ill-posed and underdetermined inverse process. A co-registered ultrasound (US) system that provides structural information about the breast lesion can improve the localization and accuracy of DOT reconstruction. Additionally, the well-known US characteristics of benign and malignant breast lesions can further improve cancer diagnosis based on DOT alone. Inspired by a fusion model deep learning approach, we combined US features extracted by a modified VGG-11 network with images reconstructed from a DOT deep learning auto-encoder-based model to form a new neural network for breast cancer diagnosis. The combined neural network model was trained with simulation data and fine-tuned with clinical data: it achieved an AUC of 0.931 (95% CI: 0.919-0.943), superior to those achieved using US images alone (0.860) or DOT images alone (0.842).

Identifiers

PMID37078047
PMCPMC10110311
OpenAlexW4323664769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.