Evidence map›Paper›PMID 37077858›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2023

Predicting left/right lung volumes, thoracic cavity volume, and heart volume from subject demographics to improve lung transplant.

Lucas Pu, Joseph K Leader, Alaa Ali, Zihan Geng, David Wilson

Open access · greenAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Understanding Machine Learning Applications in Lung Transplantation: A Narrative Review.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  8. Review
  9. Article
  10. CT-Derived Features as Predictors of Clot Burden and Resolution.Bioengineering (Basel, Switzerland) · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lucas PuNorth Allegheny High School, Wexford, Pennsylvania, United States.
Joseph K LeaderUniversity of Pittsburgh School of Medicine, Department of Radiology, Pittsburgh, Pennsylvania, United States.
Alaa AliUniversity of Pittsburgh School of Medicine, Department of Radiology, Pittsburgh, Pennsylvania, United States.ORCID https://orcid.org/0000-0001-7472-3701
Zihan GengCarnegie Mellon University, Department of Statistics and Data Science, Pittsburgh, Pennsylvania, United States.
David WilsonUniversity of Pittsburgh School of Medicine, Department of Medicine, Pittsburgh, Pennsylvania, United States.
University of Pittsburgh · USCarnegie Mellon University · US

Funding

Clinical Validation Center for Lung Cancer Early DetectionU01CA271888 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HANASH, SAMIR M · 2022 to 2025
$4.9M
Macro-vasculature: A Novel Image Biomarker of Lung CancerR01CA237277 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PU, JIANTAO · 2020 to 2024
$2.8M
NCI NIH HHS R01 CA237277NCI NIH HHS U01 CA271888
6 · The paper itself

Abstract

Purpose: Lung transplantation is the standard treatment for end-stage lung diseases. A crucial factor affecting its success is size matching between the donor's lungs and the recipient's thorax. Computed tomography (CT) scans can accurately determine recipient's lung size, but donor's lung size is often unknown due to the absence of medical images. We aim to predict donor's right/left/total lung volume, thoracic cavity, and heart volume from only subject demographics to improve the accuracy of size matching. Approach: A cohort of 4610 subjects with chest CT scans and basic demographics (i.e., age, gender, race, smoking status, smoking history, weight, and height) was used in this study. The right and left lungs, thoracic cavity, and heart depicted on chest CT scans were automatically segmented using U-Net, and their volumes were computed. Eight machine learning models [i.e., random forest, multivariate linear regression, support vector machine, extreme gradient boosting (XGBoost), multilayer perceptron (MLP), decision tree, Results: The MLP model demonstrated the best performance for predicting the thoracic cavity volume ( Conclusions: Our results demonstrate the feasibility of predicting lung, heart, and thoracic cavity volumes from subject demographics with superior performance compared with available studies in predicting lung volumes.

Indexed as

lung transplantmachine learningprediction modelingsubject demographics

Identifiers

PMID37077858
PMCPMC10108239
OpenAlexW4366088554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.