Evidence map›Paper›PMID 37077769›Full record

ReviewDrugs in context2023

Effectiveness of risankizumab in the treatment of palmoplantar psoriasis: a 52-week Italian real-life experience.

Giacomo Caldarola, Arianna Zangrilli, Gerardo Palmisano, Mauro Bavetta, Gaia Moretta, Gianluca Pagnanelli, Vincenzo Panasiti, Luca Bianchi, Clara De Simone, Ketty Peris

Open access · goldAbstract readReview
In one paragraph

Review in Drugs in context, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. IL-23 Inhibitors in Psoriasis: What Have We Learnt so Far?Journal of inflammation research · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Giacomo CaldarolaInstitute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Arianna ZangrilliDepartment of Dermatology, University of Rome Tor Vergata, Rome, Italy.
Gerardo PalmisanoInstitute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Mauro BavettaUOC Dermatologia, Ospedale San Sebastiano, Frascati (RM), Italy.
Gaia MorettaIstituto Dermopatico dell'Immacolata - IRCCS, Roma, Italy.
Gianluca PagnanelliIstituto Dermopatico dell'Immacolata - IRCCS, Roma, Italy.
Vincenzo PanasitiPlastic and Reconstructive Surgery Unit, Campus Bio-Medico University, Rome, Italy.
Luca BianchiDepartment of Dermatology, University of Rome Tor Vergata, Rome, Italy.
Clara De SimoneInstitute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Ketty PerisInstitute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Agostino Gemelli University Polyclinic · ITIstituto Dermopatico dell'Immacolata · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Rome Tor Vergata · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Data on the treatment of palmoplantar psoriasis (PP) are scarce, representing a therapeutic challenge. This study aims to assess the efficacy and safety of risankizumab in a population of patients with psoriasis with a palmoplantar involvement, over a 52-week treatment period. Methods: We performed a retrospective analysis in a cohort of patients with PP, with or without involvement of other skin sites. Palmoplantar Psoriasis Area and Severity Index (ppPASI) was assessed at baseline and after 4, 16, 28 and 52 weeks, to evaluate the PP severity. Results: Sixteen patients were enrolled. The rates of ppPASI90 responses constantly increased during the period of observation and were 18.7%, 62.2%, 75.0% and 81.2% at weeks 4, 16, 28 and 52, respectively. Only two patients suspended treatment because of ineffectiveness at week 16. Conclusion: Our data from a series of 16 patients reveal that risankizumab could represent an effective and safe therapeutic choice in patients with PP.

Indexed as

efficacyIL-23psoriasisreal-liferisankizumabsafety

Identifiers

PMID37077769
PMCPMC10108662
OpenAlexW4364369917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.