ArticleFrontiers in cardiovascular medicine2023
Atrial fibrillation as a contributor to the mortality in patients with dementia: A nationwide cohort study.
Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Association Between TNF-Alpha Levels and Atrial Fibrillation Outcomes: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Predicting common cardiovascular and non-cardiovascular outcomes after new-onset atrial fibrillation: an analysis from a UK nationwide primary-secondary care linkage dataset.European heart journal open · 2026Article
- Atrial Fibrillation Detection on the Embedded Edge: Energy-Efficient Inference on a Low-Power Microcontroller.Sensors (Basel, Switzerland) · 2025Article
- Heart failure, dementia is associated with increased stroke severity, in-hospital mortality and complications.ESC heart failure · 2025Article
- Trends in Mortality Related to Atrial Fibrillation and Dementia in Older Adults in the United States: A 2000-2020 Analysis.Journal of cardiovascular electrophysiology · 2025Article
- Associations of glycemic status with dynamic disease trajectories of atrial fibrillation and dementia.The journal of prevention of Alzheimer's disease · 2025Article
- Daytime Napping, Incident Atrial Fibrillation, and Dynamic Transitions With Dementia.JACC. Advances · 2024Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Knowledge of the risk of death in patients with dementia is essential for planning preventive strategies. This study aimed to evaluate the effect of atrial fibrillation (AF) on death risks and other factors associated with death in patients with dementia and AF. Methods: We conducted a nationwide cohort study using Taiwan's National Health Insurance Research Database. We identified subjects with dementia diagnosed for the first time and AF diagnosed concomitantly between 2013 and 2014. Subjects under the age of 18 years were excluded. Age, sex, and CHA Results: AF history was associated with higher risks of all-cause death (hazard ratio [HR]: 1.208; 95% confidence interval [CI]: 1.142-1.277) and cardiovascular death (subdistribution HR: 1.210; 95% CI: 1.077-1.359) in dementia patients than patients without a diagnosis of AF. For patients with both dementia and AF, they had a higher risk of death due to higher age, diabetes mellitus, congestive heart failure, chronic kidney disease, and prior stroke. Anti-arrhythmic drugs and novel oral anticoagulants significantly reduced the risk of death in patients with AF and dementia. Conclusion: This study found that AF is a risk factor for mortality in patients with dementia and explored several risk factors for AF-related mortality. This study highlights the importance of controlling AF especially in patients with dementia.
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