Evidence map›Paper›PMID 37077514›Full record

ReviewWorld journal of gastroenterology2023

Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature.

Endrit Shahini, Emanuele Sinagra, Alessandro Vitello, Rocco Ranaldo, Antonella Contaldo, Antonio Facciorusso, Marcello Maida

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07295405 (Effect of Water Temperature on Bowel Cleansing Quality), which is not on this map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07295405 completednot on this mapstarted 2025, after this paper: background citation

Effect of Water Temperature on Bowel Cleansing Quality: A Prospective Observational Study

Typeobservational_patient_registrySponsorBakirkoy Dr. Sadi Konuk Research and Training HospitalRan2025 to 2025Enrolled260ConditionsColonoscopy (Procedure)
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  4. Probiotics Accelerate Microbiota and Metabolic Pathway Recovery Following Colonoscopy Bowel Preparation in Ulcerative Colitis.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Endrit ShahiniGastroenterology Unit, National Institute of Gastroenterology-IRCCS "Saverio de Bellis", Castellana Grotte, Bari 70013, Italy. endrit.shahini@irccsdebellis.it.
Emanuele SinagraGastroenterology and Endoscopy Unit, Fondazione Istituto G. Giglio, Cefalù 90015, Italy.
Alessandro VitelloGastroenterology and Endoscopy Unit, S.Elia-Raimondi Hospital, Caltanissetta 93100, Italy.
Rocco RanaldoDepartment of Internal Medicine, "Mazzolani-Vandini" Hospital, Digestive Endoscopy, Ferrara 744011, Italy.
Antonella ContaldoGastroenterology Unit, National Institute of Gastroenterology "S de Bellis" Research Hospital, Bari 70013, Italy.
Antonio FacciorussoDepartment of Medical Sciences, University of Foggia, Section of Gastroenterology, Foggia 71122, Italy.
Marcello MaidaGastroenterology and Endoscopy Unit, S.Elia-Raimondi Hospital, Caltanissetta 93100, Italy.
University of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adequate bowel cleansing is critical for a high-quality colonoscopy because it affects diagnostic accuracy and adenoma detection. Nevertheless, almost a quarter of procedures are still carried out with suboptimal preparation, resulting in longer procedure times, higher risk of complications, and higher likelihood of missing lesions. Current guidelines recommend high-volume or low-volume polyethylene glycol (PEG)/non-PEG-based split-dose regimens. In patients who have had insufficient bowel cleansing, the colonoscopy should be repeated the same day or the next day with additional bowel cleansing as a salvage option. A strategy that includes a prolonged low-fiber diet, a split preparation regimen, and a colonoscopy within 5 h of the end of preparation may increase cleansing success rates in the elderly. Furthermore, even though no specific product is specifically recommended in the other cases for difficult-to-prepare patients, clinical evidence suggests that 1-L PEG plus ascorbic acid preparation are associated with higher cleansing success in hospitalized and inflammatory bowel disease patients. Patients with severe renal insufficiency (creatinine clearance < 30 mL/min) should be prepared with isotonic high volume PEG solutions. Few data on cirrhotic patients are currently available, and no trials have been conducted in this population. An accurate characterization of procedural and patient variables may lead to a more personalized approach to bowel preparation, especially in patients undergoing resection of left colon lesions, where intestinal preparation has a poor outcome. The purpose of this review was to summarize the evidence on the risk factors influencing the quality of bowel cleansing in difficult-to-prepare patients, as well as strategies to improve colonoscopy preparation in these patients.

Indexed as

CatharticsColonoscopyAgedAscorbic AcidColonHumansPolyethylene GlycolsAscorbic AcidCatharticsPolyethylene GlycolsAdenoma detection rateBowel preparationColonoscopyColorectal cancerPolyethylene glycol

Identifiers

PMID37077514
PMCPMC10107216
OpenAlexW4327629264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.