Evidence map›Paper›PMID 37077500›Full record

ArticleJournal of biomedical optics2023

Multiwavelength tissue-mimicking phantoms with tunable vessel pulsation.

Sophie Jenne, Hans Zappe

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sophie JenneUniversity of Freiburg, Department of Microsystems Engineering-IMTEK, Gisela and Erwin Sick Chair of Micro-Optics, Freiburg, Germany.ORCID 0000-0003-3158-6422
Hans ZappeUniversity of Freiburg, Department of Microsystems Engineering-IMTEK, Gisela and Erwin Sick Chair of Micro-Optics, Freiburg, Germany.ORCID 0000-0003-4603-8613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: For the development and routine characterization of optical devices used in medicine, tissue-equivalent phantoms mimicking a broad spectrum of human skin properties are indispensable. Aim: Our work aims to develop a tissue-equivalent phantom suitable for photoplethysmography applications. The phantom includes the optical and mechanical properties of the three uppermost human skin layers (dermis, epidermis, and hypodermis, each containing different types of blood vessels) plus the ability to mimic pulsation. Approach: While the mechanical properties of the polydimethylsiloxane base material are adjusted by different mixing ratios of a base and curing agent, the optical properties are tuned by adding titanium dioxide particles, India ink, and synthetic melanin in different concentrations. The layered structure of the phantom is realized using a doctor blade technique, and blood vessels are fabricated using molding wires of different diameters. The tissue-mimicking phantom is then integrated into an artificial circulatory system employing piezo-actuated double diaphragm pumps for testing. Results: The optical and mechanical properties of human skin were successfully replicated. The diameter of the artificial blood vessels is linearly dependent on pump actuation, and the time-dependent expansion profile of real pulse forms were mimicked. Conclusions: A tissue equivalent phantom suitable for the

Indexed as

Optical DevicesSkinEpidermisHumansPhantoms, ImagingPhotoplethysmographybiomedical applicationsphotoplethysmographypolydimethylsiloxanepulsationskin equivalentstissue phantom

Identifiers

PMID37077500
PMCPMC10109273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.