Evidence map›Paper›PMID 37077418›Full record

ArticleFrontiers in cell and developmental biology2023

Local injection of adipose-derived mesenchymal stem cells in silk fibroin solution on the regeneration of lower esophageal sphincter in an animal model of GERD.

Daxu Zhang, Zhanbo Wang, Lianjun Ma, Lijuan Xu, Suna Fan, Yinan Su, Xiaonan Shi, Jingjing Hu, Shuo Zhao, WeiLong Li and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Daxu ZhangDepartment of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing, China.
Zhanbo WangDepartment of Pathology, Chinese PLA General Hospital, Beijing, China.
Lianjun MaEndoscopy Center, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Lijuan XuDepartment of Gastroenterology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Suna FanState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, China.
Yinan SuDepartment of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing, China.
Xiaonan ShiThe Second Medical Center and National Clinical Research Center of Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Jingjing HuThe Second Medical Center and National Clinical Research Center of Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Shuo ZhaoThe Second Medical Center and National Clinical Research Center of Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
WeiLong LiThe Second Medical Center and National Clinical Research Center of Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Enqiang LinghuDepartment of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Li YanThe Second Medical Center and National Clinical Research Center of Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNCapital Medical University · CNDonghua University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presently, various tissue engineering methods using adult stem cells and biomaterials are being confirmed to regenerate vessels, cardiac muscle, bladder, and intestines. However, there are few studies about the repair of the lower esophageal sphincter (LES) may help alleviate the symptoms of gastroesophageal reflux disease (GERD). This study aims to determine whether Adipose-Derived Stem Cells (ADSCs) combined with regenerated silk fibroin (RSF) solution could regenerate the LES.

Indexed as

ADSCsgerdRSF solutionsmooth muscular cellstransplant

Identifiers

PMID37077418
PMCPMC10106618
OpenAlexW4362578529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.