Evidence map›Paper›PMID 37076932›Full record

ArticleBMC research notes2023

Identification of gametocyte-associated pir genes in the rodent malaria parasite, Plasmodium chabaudi chabaudi AS.

Deirdre A Cunningham, Adam J Reid, Caroline Hosking, Katrien Deroost, Irene Tumwine-Downey, Mandy Sanders, Jean Langhorne

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Deirdre A Cunningham *The Francis Crick Institute, London, UK. Deirdre.Cunningham@crick.ac.uk.
Adam J Reid *Wellcome Sanger Institute, Cambridge, UK.
Caroline HoskingThe Francis Crick Institute, London, UK.
Katrien DeroostThe Francis Crick Institute, London, UK.
Irene Tumwine-DowneyThe Francis Crick Institute, London, UK.
Mandy SandersWellcome Sanger Institute, Cambridge, UK.
Jean LanghorneThe Francis Crick Institute, London, UK.
The Francis Crick Institute · GBWellcome Sanger Institute · GB

Funding

Wellcome Trust FC001101
6 · The paper itself

Abstract

objectiveTo analyse the transcriptional profiles of the pir multigene family of Plasmodium chabaudi chabaudi in male and female gametocytes isolated from the blood of infected mice.

resultsInfected red blood cells containing female and male P. chabaudi gametocytes transcribe a distinct set of genes encoded by the multigene family pir. The overall patterns are similar to what has been observed in the close relative P. berghei, but here we show that gametocyte-associated pir genes are distinct from those involved in chronic blood-stage infection and highlight a male-associated pir gene which should be the focus of future studies.

Indexed as

MalariaParasitesPlasmodium chabaudiAnimalsFemaleMaleMiceGametocyteMultigene familyPirPlasmodium chabaudiTranscriptome

Identifiers

PMID37076932
PMCPMC10114299
OpenAlexW4366429320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.