Evidence map›Paper›PMID 37076913›Full record

ArticleJournal of medical case reports2023

Hemolysis and acquired methemoglobinemia associated with lidocaine and benzocaine topical application: a case report.

Nasim Khajavirad, Ghazal Daftari, Mehrasa Raisi Jelodar

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nasim KhajaviradDepartment of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran.
Ghazal DaftariSchool of Medicine, Tehran University of Medical Science, Keshavarz Boulevard, Tehran, 1419733141, Iran. Ghazaal.daftari@gmail.com.
Mehrasa Raisi JelodarͨBabol University of Medical Science, Babol, Iran.
University of Tehran · IRBabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTopical anesthetics are commonly used over the counter, and one of the adverse effects of these medications is methemoglobinemia, which is a serious and life-threatening condition. CASE PRESENTATION: We describe a 25-year-old Persian male presenting with generalized weakness, dizziness, headache, and cyanosis. In addition, he had genital warts starting 3 weeks ago, which were self-treated with podophyllin, resulting in itching and pain. He used over-the-counter topical anesthetics, including benzocaine and lidocaine, to reduce the symptoms. According to the lab data, signs and symptoms of methemoglobinemia and hemolysis were diagnosed. Considering the hemolysis, ascorbic acid was used for treatment. The patient was discharged after 5 days with normal arterial blood gas and pulse oximetry and no signs and symptoms.

conclusionThis case highlights that self-administration of some topical anesthetics may lead to potentially fatal conditions.

Indexed as

BenzocaineMethemoglobinemiaAdultAnesthetics, LocalHemolysisHumansLidocaineMaleMethylene BlueAnesthetics, LocalBenzocaineLidocaineMethylene BlueBenzocaineHemolysisLidocaineMethemoglobinTopical anesthetics

Identifiers

PMID37076913
PMCPMC10116714
OpenAlexW4366364972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.