Evidence map›Paper›PMID 37076904›Full record

ArticleBMC chemistry2023

Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles: comprehensive spectroscopic study.

Ahmed Faried Abdel Hakiem, Ahmed Mohsen Kamal El-Sagheir, Mohammed E Draz, Niveen A Mohamed, Ahmed Safwat Aboraia

Open access · goldAbstract read
In one paragraph

Article in BMC chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ahmed Faried Abdel HakiemPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, South Valley University, Qena, 83523, Egypt. ahmed_faried@pharm.kfs.edu.eg.
Ahmed Mohsen Kamal El-SagheirMedicinal Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, 71516, Egypt.
Mohammed E DrazDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 11152, Egypt.
Niveen A MohamedDepartment of Pharmaceutical Chemistry, Unaizah College of Pharmacy, Qassim University, Unaizah, 5888, Saudi Arabia.
Ahmed Safwat AboraiaMedicinal Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, 71516, Egypt.
Assiut University · EGDelta University for Science and Technology · EGQassim University · SASouth Valley University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The direct binding of antiviral agents; Daclatasvir and valacyclovir and green synthesized nanoparticles to salmon sperm DNA have been assessed in a comparative study. The nanoparticles were synthesized by the hydrothermal autoclave method and have been fully characterized. The interactive behavior and competitive binding of the analytes to DNA in addition to the thermodynamic properties were deeply investigated by the UV-visible spectroscopy. The binding constants were monitored in the physiological pH conditions to be 1.65 × 10

Indexed as

An in-depth UV–visible spectroscopic investigationDaclatasvir and valacyclovir, Nitrogen doped orange quantum dotsMolecular modellingThe electrostatic and non-electrostatic kinetic parameters

Identifiers

PMID37076904
PMCPMC10114480
OpenAlexW4366413457

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.