Evidence map›Paper›PMID 37076883›Full record

ArticlePerioperative medicine (London, England)2023

Non-intubated deep paralysis: a new anaesthesia strategy for vocal cord polypectomy.

Yichen Fan, Xiaoying Chi, Danyan Zhu, Jiemin Yin, Yaling Liu, Diansan Su

Registry-linked trialAbstract read
In one paragraph

Article in Perioperative medicine (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04247412 (Laryngomicrosurgery Under Nonintubated Deep Paralysis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04247412 unknown statusnot on this map

Laryngomicrosurgery Under Nonintubated Deep Paralysis (NIDP) General Anesthesia Supported by Transnasal Humidified Rapid-insufflation Ventilatory Exchange: A Case Series Study

TypeobservationalSponsorRenJi HospitalRan2020 to 2021Enrolled20ConditionsVocal Polyp
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yichen FanDepartment of Anesthesiology, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiaoying ChiDepartment of Anesthesiology, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China.
Danyan ZhuNursing department, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China.
Jiemin YinDepartment of Anesthesiology, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yaling LiuDepartment of Anesthesiology, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China.
Diansan SuDepartment of Anesthesiology, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China. diansansu@yahoo.com.

Funding

National Natural Science Foundation of China 81771133, 81970995, U21A20357Renji Hospital Clinical Innovation Foundation PYII20-09,RJTJ-JX-002,RJPY-DZX-007Shanghai municipal Education Commission-Gaofeng Clinical Medicine Support 20191903Shanghai Municipal Science and Technology Commission Founding 21S31900100Shanghai Shenkang Founding SHDC22020208
6 · The paper itself

Abstract

backgroundVocal cord polyp is common otorhinolaryngological disease, traditionally treated by vocal cord polypectomy under a supporting laryngoscope with general anaesthesia. Although it is safe and controllable, it would cause some anaesthesia complications. Moreover, the complex process of general anaesthesia may significantly reduce surgical efficiency. Avoiding these problems remains an important issue.

methodsAll patients were subjected to the standard non-intubated deep paralysis (NIDP) protocol consisting of four phases. An emergency plan was launched when NIDP cannot be implemented successfully. Patient characteristics, blood gas and monitoring data were collected during NIDP. Data concerning satisfaction, complications and duration of anaesthesia and recovery were collected to assess its effectiveness.

resultAmong 20 enrolled patients, the success rate of NIDP was 95%. Only one patient failed in completing NIDP. Blood gas analysis revealed that the partial pressure of oxygen and carbon dioxide was maintained at safe levels. Monitoring during NIDP revealed fluctuations in mean arterial pressure between 110 and 70 mmHg, and the heart rate was stable at 60-100 beats per minute. The duration of anaesthesia and postoperative recovery were 13.0 ± 2.84 and 5.47 ± 1.97 min, respectively. All patients and surgeons were satisfied with NIDP, and no complications were detected before discharge.

conclusionNIDP can be safely applied to patients and can replace general anaesthesia in vocal cord polypectomy. It can significantly reduce the duration of anaesthesia and postoperative recovery. No anaesthesia complications occurred without intubation, and patients and surgeons were satisfied with NIDP. TRIAL REGISTRATIONS: This single-centre, prospective study was registered on clinicaltrial.gov (NCT04247412) on 30

Indexed as

High-flow nasal oxygenationInnovative anaesthesia strategyMicro-laryngoscopic surgeryMuscle relaxationNon-intubated deep paralysis

Identifiers

PMID37076883
PMCPMC10116817

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.