ArticleBMC pregnancy and childbirth2023
The Effect of 2016 Chinese second-child policy and different maternal age on pregnancy outcomes in Hebei Province, China.
Article in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Prevalence of placenta previa among deliveries: An update systematic review and meta-analysis after the introduction of the two-child policy in Mainland China.Journal of global health · 2024Pooled it
- Dnmt3a-mediated abnormal DNA methylation is associated with myelination deficits in offspring of advanced maternal age rats.Molecular biology reports · 2026Article
- Assessing the impact of China's universal two-child policy on infant health: evidence from a quasi-experimental study.European journal of public health · 2026Article
- Comparison status and factors of pregnancy stress among pregnant women with second child between advanced maternal age and reproductive age: a cross-sectional study.BMC pregnancy and childbirth · 2026Article
- Prediction of hypertensive disorders of pregnancy in advanced-age pregnant women using SHAP value and XGBoost.Scientific reports · 2026Article
- Obstetric characteristics and pregnancy outcomes under China's three-child policy: a retrospective cohort study.Frontiers in global women's health · 2026Article
- Temporal trend and influencing factors of high-risk pregnancy in China: a nationwide longitudinal analysis.Frontiers in public health · 2026Article
- Association of maternal serum vitamin a levels in the first trimester with the risk of adverse pregnancy outcomes: a prospective cohort study of Chinese women.Frontiers in nutrition · 2026Article
- Association between the serum uric acid-to-creatinine ratio index and the risk of preeclampsia in advanced maternal age pregnant women: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Evaluation and dynamic evolution of maternal and child health services in township health centers in ethnic minority areas of Guangxi, China.Primary health care research & development · 2025Article
- Association of Ambient Air Pollution and Temperature Exposure with Placental Abruption: A Nested Case-Control Study Based on Live Birth Registrations.Environmental health perspectives · 2025Article
- Advanced maternal age elevates the prevalence of hypertensive disorders in women of Japanese, independent of blood pressure: a study from the Japan Environment and Children's study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Impact of maternal age on birth weight-related adverse outcomes in newborns: a retrospective study in south-central China.BMC pregnancy and childbirth · 2025Article
- An explainable machine learning model for predicting preterm birth in pregnant women with gestational diabetes mellitus and hypertensive disorders of pregnancy: development and external validation.Frontiers in endocrinology · 2025Article
- Risk Factors for Gestational Diabetes Mellitus in Mainland China: A Systematic Review and Meta-Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Impact of Prior Cesarean Delivery on Pregnancy Outcomes and Hemorrhage Risks in Complete Placenta Previa: A Decade-Long Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Changes in Maternal Socio-Demographic Characteristics and Pregnancy Outcomes Across Monitoring Regions - Six Provinces, China, 2016-2022.China CDC weekly · 2024Article
- Trajectories tracking of maternal and neonatal health in eastern China from 2010 to 2021: A multicentre cross-sectional study.Journal of global health · 2024Article
- Article
- Changes in the characteristics and outcomes of high-risk pregnant women who delivered prior to and after China's universal two-child policy: a real-world retrospective study, 2010-2021.BMC public health · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo explore the effect of the 2016 Chinese second child policy and different maternal ages on adverse perinatal outcomes.
methodsClinical data were collected from 22 monitoring hospitals in Hebei Province from January 1, 2013, to December 31, 2021. A total of 413,892 parturient were divided into 3 groups based on delivery age: 20-34, 35-39, and 40-55 years old. The clinical data were analyzed to explore the relationship among the 2016 Chinese second-child policy, maternal age, and various pregnancy risks.
resultsPregnancy complications showed an upward trend from 2013 to 2021.The top 10 incidences of pregnancy complications in Hebei Province were anemia, small for gestational age (SGA), large for gestational age (LGA), macrosomia, gestational diabetes mellitus (GDM), premature delivery, preeclampsia (PE), postpartum hemorrhage (PPH), placenta previa, and placental abruption. The two-child policy was implemented in 2016. The incidence of pregnancy complications, anemia, GDM, PE, placental abruption, cesarean delivery, premature delivery, SGA, LGA, macrosomia in 2016-2021 was significantly higher than that in 2013-2015 (P<0.05), and the proportion of women of advanced maternal age (AMA, ≥ 35 years old) increased from 2013 to 2021. Advanced maternal age was a risk factor for most assessed adverse pregnancy outcomes, including GDM, PE, placenta previa, placenta abruption, cesarean delivery, PPH, premature delivery, SGA, LGA and macrosomia.
conclusionAfter the adjustment of the "second-child" policy, the incidence of pregnancy complications increased. Moreover, the risk of adverse pregnancy outcomes in AMA has increased. Early prevention and intervention should be implemented to cope with the occurrence of adverse perinatal outcomes.
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